Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14290105 | 0.86 | MAOA (0.40) | MAOAMAOB | |
| SCHEMBL14050228 | 0.86 | PARP1 (0.41) | MAOAMAOBPARP1L3MBTL1NPC1 | |
| SCHEMBL6838708 | 0.84 | PARP1 (0.43) | MAOBPARP1L3MBTL1NPC1ALDH1A1 | |
| SCHEMBL18656435 | 0.82 | MAOA (0.38) | MAOAMAOBPARP1ALDH1A1 | |
| SCHEMBL7421095 | 0.82 | MAOA (0.42) | MAOAMAOB | |
| SCHEMBL18642103 | 0.82 | MAOA (0.42) | MAOAMAOB | |
| SCHEMBL18656438 | 0.81 | MAOA (0.40) | MAOAMAOBPARP1SMN1; SMN2 | |
| SCHEMBL29506700 | 0.81 | HTR2A (0.44) | ALDH1A1LMNA | |
| SCHEMBL28695323 | 0.81 | HTR2A (0.44) | ALDH1A1LMNA | |
| SCHEMBL16667216 | 0.78 | MAPT (0.50) | MAOAMAOBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721947-B1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-03-14 | — | — | EP | disclosed |
| US-5703121-A | SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-12-30 | — | — | US | disclosed |
| EP-0721947-A1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-07-17 | — | — | EP | disclosed |