Methacrylic Acid

Methacrylic Acid

SCHEMBL7752935

C=C(C)C(=O)O.C=C(C)C(=O)O.O=C(O)c1ccccc1C(=O)OCCO

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.51
TSHR P16473 8/20 0.50
TDP1 Q9NUW8 4/20 0.49
L3MBTL1 Q9Y468 3/20 0.49
CYP3A4 P08684 4/20 0.47
MAPK1 P28482 3/20 0.47
TP53 P04637 2/20 0.47
LMNA P02545 1/20 0.46
ALOX15 P16050 1/20 0.42
SCN1A P35498 2/20 0.42
SCN2A Q99250 2/20 0.42
SCN3A Q9NY46 2/20 0.42
TARBP2 Q15633 1/20 0.41
HSD17B10 Q99714 2/20 0.40
NPC1 O15118 1/20 0.40
GLA P06280 1/20 0.40
HPGD P15428 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HIF1A Q16665 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL31536439 1.00 ALDH1A1 (0.51) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
Methacrylic Acid SCHEMBL1260612 1.00 ALDH1A1 (0.51) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
Methacrylic Acid SCHEMBL25277352 0.95 ALDH1A1 (0.56) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
Methacrylic Acid SCHEMBL4783603 0.93 TSHR (0.48) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
Methacrylic Acid SCHEMBL1720322 0.92 TSHR (0.49) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
Ethylene SCHEMBL5534814 0.89 ALDH1A1 (0.59) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL159456 0.89 ALDH1A1 (0.62) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL29668022 0.89 ALDH1A1 (0.62) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
O-Xylene SCHEMBL28359411 0.89 ALDH1A1 (0.42) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
Water SCHEMBL11188129 0.87 ALDH1A1 (0.61) ALDH1A1TSHRTDP1L3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0705859-B1 Polyester prepolymer showing shape-memory effect TONG YANG NYLON CO LTD (KR) 2001-03-14 EP disclosed