Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2437915 | 0.90 | L3MBTL1 (0.59) | SMN1; SMN2L3MBTL1HPGDLMNAMAPT | |
| SCHEMBL3382930 | 0.89 | L3MBTL1 (0.59) | SMN1; SMN2L3MBTL1HPGDLMNAFFAR1 | |
| SCHEMBL11824190 | 0.89 | KMT2A (0.56) | SMN1; SMN2L3MBTL1HPGDLMNAFFAR1 | |
| Succinic Acid Diethyl Ester SCHEMBL27940678 | 0.88 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL17789175 | 0.88 | SMN1; SMN2 (0.66) | SMN1; SMN2L3MBTL1HPGDLMNAFFAR1 | |
| SCHEMBL11827120 | 0.87 | KMT2A (0.57) | SMN1; SMN2L3MBTL1HPGDRAB9AMAPT | |
| SCHEMBL15058334 | 0.86 | ERCC5 (0.51) | SMN1; SMN2L3MBTL1HPGDLMNAFFAR1 | |
| SCHEMBL11834763 | 0.86 | KMT2A (0.60) | SMN1; SMN2L3MBTL1HPGDLMNARAB9A | |
| SCHEMBL11757752 | 0.86 | KMT2A (0.63) | SMN1; SMN2L3MBTL1HPGDLMNAFFAR1 | |
| SCHEMBL4270804 | 0.85 | MAPT (0.61) | SMN1; SMN2L3MBTL1HPGDLMNAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0769015-B1 | PHOSPHONIC ACID COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-03-14 | — | — | EP | disclosed |
| US-5716944-A | USEFUL AS PROPHYLACTIC AND THERAPEUTIC AGENTS OF VARIOUS METABOLIC BONE DISEASES SUCH AS OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0769015-A1 | PHOSPHONIC ACID COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-04-23 | — | — | EP | disclosed |
| WO-1996001267-A1 | PHOSPHONIC ACID COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-18 | — | — | WO | disclosed |
| EP-0267734-B1 | Chemical compounds | ZENECA LTD (GB) | 1994-01-26 | — | — | EP | disclosed |
| US-4877811-A | FUNGICIDES, INSECTICIDES, MITICIDES, PLANTH GROWTH REGULATORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-10-31 | — | — | US | disclosed |
| EP-0267734-A2 | Chemical compounds | ZENECA LIMITED (GB) | 1988-05-18 | — | — | EP | disclosed |