Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7753078 | 1.00 | GRM2 (0.40) | GRM2CYP3A4CYP2C9KDM1ARCOR1 | |
| SCHEMBL7753060 | 0.93 | GRM2 (0.39) | GRM2CYP3A4CYP2C9KDM1ARCOR1 | |
| SCHEMBL7753057 | 0.93 | GRM2 (0.39) | GRM2CYP3A4CYP2C9KDM1ARCOR1 | |
| SCHEMBL8538286 | 0.91 | FFAR4 (0.38) | GRM2KDM1ARCOR1FFAR4FFAR1 | |
| SCHEMBL8538287 | 0.91 | FFAR4 (0.38) | GRM2KDM1ARCOR1FFAR4FFAR1 | |
| SCHEMBL7773877 | 0.88 | GRM2 (0.40) | GRM2CYP3A4CYP2C9FFAR4FFAR1 | |
| SCHEMBL7773875 | 0.88 | GRM2 (0.40) | GRM2CYP3A4CYP2C9FFAR4FFAR1 | |
| SCHEMBL7759077 | 0.87 | CTSK (0.36) | GRM2CYP3A4CYP2C9KDM1AAPP | |
| SCHEMBL8017659 | 0.87 | GRM2 (0.36) | GRM2CYP3A4CYP2C9KDM1ARCOR1 | |
| SCHEMBL8017658 | 0.87 | GRM2 (0.36) | GRM2CYP3A4CYP2C9KDM1ARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718387-B1 | A liquid crystal composition and a liquid crystal display element which contains it | SHINETSU CHEMICAL CO (JP) | 2001-03-14 | — | — | EP | disclosed |
| EP-0650969-B1 | A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5762826-A | Liquid crystal composition and a liquid crystal display element which contains it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| US-5730901-A | Silacyclohexane compounds, preparation thereof liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0799878-A1 | Liquid crystal compositions and liquid crystal display elements containing same | Shin-Etsu Chemical Co., Ltd. (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-5659059-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0718387-A1 | A liquid crystal composition and a liquid crystal display element which contains it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |
| EP-0650969-A1 | A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-05-03 | — | — | EP | disclosed |