SCHEMBL7753101

SCHEMBL7753101

CCCCCCC[SiH]1CCC(CCc2ccc(F)cc2)CC1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.42
PSMD14 O00487 1/20 0.38
HSP90AA1 P07900 1/20 0.38
MMP2 P08253 1/20 0.38
MC4R P32245 1/20 0.38
RAD52 P43351 1/20 0.38
MAOA P21397 1/20 0.36
SPHK1 Q9NYA1 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7753104 1.00 MAOB (0.42) MAOBPSMD14HSP90AA1MMP2MC4R
SCHEMBL7755798 0.99 MAOB (0.43) MAOBPSMD14HSP90AA1MMP2MC4R
SCHEMBL7755794 0.99 MAOB (0.43) MAOBPSMD14HSP90AA1MMP2MC4R
SCHEMBL7771579 0.95 MAOB (0.40) MAOBMAOA
SCHEMBL7771574 0.95 MAOB (0.40) MAOBMAOA
SCHEMBL7762600 0.92 ITGB3 (0.41) SPHK1
SCHEMBL7762593 0.92 ITGB3 (0.41) SPHK1
SCHEMBL8436282 0.91 MAOB (0.38) MAOBPSMD14HSP90AA1MMP2MC4R
SCHEMBL8436278 0.91 MAOB (0.38) MAOBPSMD14HSP90AA1MMP2MC4R
SCHEMBL8012354 0.91 MAOB (0.40) MAOBPSMD14HSP90AA1MMP2MC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718387-B1 A liquid crystal composition and a liquid crystal display element which contains it SHINETSU CHEMICAL CO (JP) 2001-03-14 EP disclosed
US-5762826-A Liquid crystal composition and a liquid crystal display element which contains it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-06-09 US disclosed
EP-0718387-A1 A liquid crystal composition and a liquid crystal display element which contains it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-06-26 EP disclosed