SCHEMBL7753347

SCHEMBL7753347

NC(=O)CN1CCCN(CC(N)=O)CCN(CC(N)=O)CCCNCC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 5/20 0.47
CHRM5 P08912 2/20 0.46
CHRM3 P20309 2/20 0.46
KDM4E B2RXH2 2/20 0.46
CXCR4 P61073 6/20 0.44
ALDH1A1 P00352 1/20 0.41
POLB P06746 1/20 0.41
PKM P14618 1/20 0.41
TSHR P16473 1/20 0.41
MEN1 O00255 1/20 0.40
CHRM2 P08172 1/20 0.40
CHRM1 P11229 1/20 0.40
ADRA2C P18825 1/20 0.40
CCR2 P41597 1/20 0.40
CXCL12 P48061 1/20 0.40
BLM P54132 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15043632 0.98 SIGMAR1 (0.48) SIGMAR1CHRM5CHRM3KDM4ECXCR4
SCHEMBL1555048 0.96 SIGMAR1 (0.49) SIGMAR1CHRM5CHRM3KDM4ECXCR4
SCHEMBL28997085 0.93 CXCR4 (0.53) SIGMAR1CHRM5CHRM3KDM4ECXCR4
SCHEMBL23014609 0.90 KDM4E (0.54) SIGMAR1CHRM5CHRM3KDM4EALDH1A1
SCHEMBL13833227 0.88 KDM4E (0.56) SIGMAR1CHRM5CHRM3KDM4EALDH1A1
SCHEMBL422666 0.88 KDM4E (0.56) SIGMAR1CHRM5CHRM3KDM4EALDH1A1
Hydrochloric Acid SCHEMBL4681 0.86 KDM4E (0.54) SIGMAR1CHRM5CHRM3KDM4EALDH1A1
SCHEMBL3832605 0.86 KDM4E (0.54) SIGMAR1CHRM5CHRM3KDM4ECXCR4
Hydrochloric Acid SCHEMBL1546636 0.86 KDM4E (0.54) SIGMAR1CHRM5CHRM3KDM4EALDH1A1
SCHEMBL10615036 0.86 KDM4E (0.54) SIGMAR1CHRM5CHRM3KDM4ECXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8975395-B2 Materials for the solid/liquid extraction of heavy metal ions, containing supported N-functionalized polyazacycloalkanes CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2015-03-10 US disclosed
WO-2009112736-A1 MATERIALS FOR THE SOLID/LIQUID EXTRACTION OF HEAVY METAL IONS, CONTAINING SUPPORTED N-FUNCTIONALISED POLYAZACYCLOALKANES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) 2009-09-17 WO disclosed
WO-2001046202-A1 POLYAZACYCLOALKANES, ORGANOMETALLIC COMPLEXES THAT INCORPORATE THEM AS LIGANDS AND THE USE OF SAID COMPOUNDS IN THE EXTRACTION OF HEAVY METALS L'AIR LIQUIDE SOCIETE ANONYME A DIRECTOIRE ET CONSEIL DE SURVEILLANCE POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2001-06-28 WO disclosed