Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.61 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.48 |
| ▸ | PARP11 | Q9NR21 | 4/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19574541 | 0.84 | PARP11 (0.55) | PARP10PARP11GABRG2GABRB3GABRA5 | |
| SCHEMBL22815609 | 0.83 | BRD4 (0.82) | BRD4PDE3BPDE3APDK2P2RY12 | |
| SCHEMBL21052076 | 0.81 | BRD4 (0.71) | BRD4PDE3BPDE3APDK2MAOA | |
| SCHEMBL8682850 | 0.79 | BRD4 (0.61) | BRD4PDE3BPDE3APDK2P2RY12 | |
| SCHEMBL1036450 | 0.79 | KCNA5 (0.53) | PARP10PARP11GABRG2GABRB3GABRA5 | |
| SCHEMBL1239440 | 0.78 | PARP11 (0.50) | PARP10PARP11GABRG2GABRB3GABRA5 | |
| SCHEMBL12502481 | 0.78 | PARP11 (0.48) | PARP10PARP11GABRG2GABRB3GABRA5 | |
| SCHEMBL9133347 | 0.77 | BRD4 (0.65) | BRD4PDE3BPDE3APDK2P2RY12 | |
| SCHEMBL11603017 | 0.76 | PDE3B (0.63) | BRD4PDE3BPDE3APDK2P2RY12 | |
| Hydrochloric Acid SCHEMBL12502617 | 0.75 | PARP11 (0.50) | PARP10PARP11GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725059-B1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMA (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-6048854-A | ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |