SCHEMBL1036450

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6583935	0.92	MAOB (0.47)	KCNA5PARP11PARP10DRD2MAOB
	SCHEMBL1037269	0.89	DRD2 (0.56)	KCNA5PARP11PARP10DRD2PARP1
	SCHEMBL19574541	0.89	PARP11 (0.55)	KCNA5PARP11PARP10GABRG2GABRB3
	SCHEMBL1239440	0.87	PARP11 (0.50)	KCNA5PARP11PARP10GABRG2GABRB3
	SCHEMBL4728129	0.85	GRM5 (0.42)	KCNA5DRD2MAOBGRM5
	SCHEMBL1038435	0.84	DRD2 (0.57)	KCNA5PARP11PARP10DRD2PARP1
	Hydrochloric Acid SCHEMBL12502617	0.84	PARP11 (0.50)	KCNA5PARP11PARP10GABRG2GABRB3
	SCHEMBL4729073	0.81	DRD2 (0.43)	KCNA5DRD2MAOBGRM5
	SCHEMBL5100387	0.81	HRH3 (0.72)	DRD2MAOB
	SCHEMBL21040262	0.80	PARP11 (0.55)	KCNA5PARP11PARP10GABRG2GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.