Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.35 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7753371 | 0.80 | ITGB3 (0.49) | F2PLAUITGB3ITGA2B | |
| SCHEMBL27464157 | 0.80 | ITGB3 (0.49) | F2PLAUITGB3ITGA2B | |
| SCHEMBL27462386 | 0.67 | F2 (0.43) | HPGDPRSS1TMPRSS2LMNASMN1; SMN2 | |
| SCHEMBL27547990 | 0.66 | ITGB3 (0.66) | ITGB3ITGA2B | |
| SCHEMBL7752535 | 0.66 | ITGB3 (0.66) | ITGB3ITGA2B | |
| SCHEMBL27464574 | 0.66 | F2 (0.45) | PRSS1TMPRSS2PRMT1F2ST14 | |
| SCHEMBL27547987 | 0.66 | MEN1 (0.43) | HPGDPRSS1TMPRSS2LMNAMEN1 | |
| SCHEMBL27450345 | 0.65 | F2 (0.48) | PRSS1TMPRSS2F2ITGB3ITGA2B | |
| SCHEMBL27547991 | 0.65 | CYP1A2 (0.42) | ALDH1A1HPGDGAAPRSS1TMPRSS2 | |
| SCHEMBL14426997 | 0.64 | ITGB3 (0.65) | PRSS1F10ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725059-B1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMA (JP) | 2001-01-17 | — | — | EP | disclosed |