3-Chloro-Cinnamic Acid

3-Chloro-Cinnamic Acid

SCHEMBL7753489

O=C(O)C=Cc1cccc(Cl)c1.O=C(O)C=Cc1ccccc1Cl

nearest known ligand 0.60

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.60
CYP1A2 P05177 2/20 0.59
CYP2C9 P11712 1/20 0.59
LMNA P02545 1/20 0.56
ITGB2 P05107 2/20 0.52
ICAM1 P05362 2/20 0.52
ITGAL P20701 2/20 0.52
PTGER3 P43115 2/20 0.52
PTGER2 P43116 2/20 0.52
MAPT P10636 2/20 0.52
TBXA2R P21731 1/20 0.52
PTGFR P43088 1/20 0.52
PTGIR P43119 1/20 0.52
PTGDR Q13258 1/20 0.52
PLA2G1B P04054 1/20 0.52
ATG4B Q9Y4P1 1/20 0.52
HDAC1 Q13547 2/20 0.51
HDAC8 Q9BY41 2/20 0.51
HDAC6 Q9UBN7 2/20 0.51
HDAC3 O15379 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-Chloro-Cinnamic Acid SCHEMBL79591 0.87 CYP1A2 (0.76) MAOBCYP1A2CYP2C9LMNAITGB2
3-Chloro-Cinnamic Acid SCHEMBL79592 0.87 CYP1A2 (0.76) MAOBCYP1A2CYP2C9LMNAITGB2
3-Chloro-Cinnamic Acid SCHEMBL22396853 0.87 CYP1A2 (0.76) MAOBCYP1A2CYP2C9LMNAITGB2
3-Chloro-Cinnamic Acid SCHEMBL9632314 0.86 CYP1A2 (0.73) MAOBCYP1A2CYP2C9LMNAITGB2
3-Chloro-Cinnamic Acid SCHEMBL11469853 0.86 CYP1A2 (0.73) MAOBCYP1A2CYP2C9LMNAITGB2
SCHEMBL7757694 0.86 CYP1A2 (0.56) MAOBCYP1A2CYP2C9LMNAMAPT
SCHEMBL29393232 0.84 HDAC1 (0.65) MAOBCYP1A2LMNAITGB2ICAM1
SCHEMBL322878 0.84 HDAC1 (0.65) MAOBCYP1A2LMNAITGB2ICAM1
SCHEMBL211297 0.84 HDAC1 (0.65) MAOBCYP1A2LMNAITGB2ICAM1
SCHEMBL12852987 0.84 HDAC1 (0.65) MAOBCYP1A2LMNAITGB2ICAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6289286-B1 Surface regeneration of biosensors and characterization of biomolecules associated therewith BIACORE AB (SE) 2001-09-11 US claimed
EP-1082607-A1 SURFACE REGENERATION OF BIOSENSORS Biacore AB (SE) 2001-03-14 EP claimed
WO-1999063333-A1 SURFACE REGENERATION OF BIOSENSORS BIACORE AB (SE) 1999-12-09 WO claimed
EP-1082607-A1 SURFACE REGENERATION OF BIOSENSORS Biacore AB (SE) 2001-03-14 EP disclosed
WO-1999063333-A1 SURFACE REGENERATION OF BIOSENSORS BIACORE AB (SE) 1999-12-09 WO disclosed