Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.54 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.54 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.49 |
| ▸ | ALOX5AP | P20292 | 7/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9121462 | 0.99 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2GPBAR1ALOX5APFFAR1 | |
| SCHEMBL9360601 | 0.88 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2GPBAR1ALOX5APFFAR1 | |
| SCHEMBL9364857 | 0.87 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2GPBAR1ALOX5APFFAR1 | |
| SCHEMBL7752204 | 0.87 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2GPBAR1ALOX5APFFAR1 | |
| SCHEMBL7751498 | 0.87 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2GPBAR1ALOX5APFFAR1 | |
| SCHEMBL7751238 | 0.87 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2GPBAR1ALOX5APFFAR1 | |
| SCHEMBL7751505 | 0.87 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2GPBAR1ALOX5APFFAR1 | |
| SCHEMBL9360073 | 0.86 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2GPBAR1ALOX5APFFAR1 | |
| SCHEMBL9364595 | 0.85 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2GPBAR1ALOX5APFFAR1 | |
| SCHEMBL7746715 | 0.85 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2GPBAR1ALOX5APFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001035936-A2 | USE OF SUBSTITUTED (QUINOLIN-2-YL-METHOXY)PHENYL-ACYL-SULPHONAMIDES AND -CYANAMIDES FOR THE TREATMENT OF DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-25 | — | — | WO | disclosed |
| US-5091392-A | Enzyme inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |