Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.52 |
| ▸ | ALOX5AP | P20292 | 8/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364857 | 0.99 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2ALOX5APGPBAR1ALOX5 | |
| SCHEMBL7751505 | 0.99 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2ALOX5APGPBAR1ALOX5 | |
| SCHEMBL7751498 | 0.99 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2ALOX5APGPBAR1ALOX5 | |
| SCHEMBL7752204 | 0.99 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2ALOX5APGPBAR1ALOX5 | |
| SCHEMBL7751238 | 0.99 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2ALOX5APGPBAR1ALOX5 | |
| SCHEMBL7753530 | 0.88 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2ALOX5APGPBAR1ALOX5 | |
| SCHEMBL9360073 | 0.88 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2ALOX5APGPBAR1ALOX5 | |
| SCHEMBL9360324 | 0.88 | CYSLTR2 (0.51) | CYSLTR1CYSLTR2ALOX5APGPBAR1ALOX5 | |
| SCHEMBL7751226 | 0.88 | CYSLTR2 (0.57) | CYSLTR1CYSLTR2ALOX5APGPBAR1ALOX5 | |
| SCHEMBL7746715 | 0.87 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2ALOX5APGPBAR1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399291-B1 | Substituted (Quinoline-2-yl-methoxy)phenyl-acyl-sulphonamides and cyanamides , process for their preparation and their use in medicines | BAYER AG (DE) | 1994-07-20 | — | — | EP | disclosed |
| US-5091392-A | Enzyme inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |