Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ICMT | O60725 | 1/20 | 0.35 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11366464 | 0.84 | NPSR1 (0.39) | GAAKMT2AF2RALDH1A1TSHR | |
| SCHEMBL251685 | 0.84 | NPSR1 (0.39) | GAAKMT2AF2RALDH1A1TSHR | |
| SCHEMBL817511 | 0.84 | NPSR1 (0.39) | GAAKMT2AF2RALDH1A1TSHR | |
| SCHEMBL31169458 | 0.81 | HSPA5 (0.40) | KMT2AMEN1F2RALDH1A1HTT | |
| SCHEMBL6049914 | 0.81 | TDP1 (0.38) | GAAKMT2AF2RALDH1A1HTT | |
| SCHEMBL27151260 | 0.79 | ALDH1A1 (0.42) | GAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL30763877 | 0.79 | NPSR1 (0.42) | GAAKMT2AALDH1A1SMN1; SMN2PTGS2 | |
| SCHEMBL331015 | 0.79 | NPSR1 (0.42) | GAAKMT2AALDH1A1SMN1; SMN2PTGS2 | |
| SCHEMBL299811 | 0.78 | GAA (0.69) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6659431 | 0.78 | F2R (0.36) | GAAKMT2AF2RLMNAHSPA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001048057-A1 | MULTIFUNCTIONAL THERMO-OXIDATIVE STABILISER | DSM N.V. (NL) | 2001-07-05 | — | — | WO | disclosed |