SCHEMBL7753563

SCHEMBL7753563

COC=C(Oc1cccc(OCc2ccccc2Cl)c1C(=O)O)C(=O)OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 3/20 0.46
FABP5 Q01469 3/20 0.46
TP53 P04637 1/20 0.44
HTT P42858 1/20 0.44
NR4A2 P43354 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 1/20 0.42
HDAC8 Q9BY41 2/20 0.42
MCL1 Q07820 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA1D P25100 1/20 0.41
ADRA1A P35348 1/20 0.41
ADRA1B P35368 1/20 0.41
SLC1A5 Q15758 1/20 0.41
HPGD P15428 1/20 0.40
FOLH1 Q04609 2/20 0.40
MEN1 O00255 1/20 0.40
SLC26A4 O43511 1/20 0.40
KMT2A Q03164 1/20 0.40
FFAR1 O14842 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7753560 1.00 FABP4 (0.46) FABP4FABP5TP53HTTNR4A2
SCHEMBL7754241 0.84 FOLH1 (0.40) NR4A2NPC1RAB9AFOLH1MEN1
SCHEMBL7754234 0.84 FOLH1 (0.40) NR4A2NPC1RAB9AFOLH1MEN1
SCHEMBL7803906 0.84 CA12 (0.41) FABP4HPGDKMT2AMAPT
SCHEMBL7803904 0.84 CA12 (0.41) FABP4HPGDKMT2AMAPT
SCHEMBL7753646 0.83 SMN1; SMN2 (0.43) NR4A2NPC1RAB9AMEN1KMT2A
SCHEMBL7753650 0.83 SMN1; SMN2 (0.43) NR4A2NPC1RAB9AMEN1KMT2A
SCHEMBL7754517 0.82 CA12 (0.51) FABP4HPGD
SCHEMBL7795814 0.82 CA12 (0.51) FABP4HPGD
SCHEMBL7754513 0.82 CA12 (0.51) FABP4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010029239-A1 New herbicidal compositions CRAMP MICHAEL COLIN (GB) 2001-10-11 US disclosed
WO-2001047863-A2 NEW HERBICIDAL COMPOSITIONS AVENTIS CROPSCIENCE SA (FR) 2001-07-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010029239-A1 New herbicidal compositions DDT, CYP1B1, CYP4X1 FABP4 3540/4885FABP5 2631/4885TP53 4300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.