Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20507373 | 0.88 | LIPG (0.38) | LIPGTLR8TSHR | |
| O-Xylene SCHEMBL27745912 | 0.81 | TSHR (0.48) | TLR8TSHRACHE | |
| SCHEMBL9511768 | 0.81 | TAAR1 (0.50) | TAAR1CHRM2KMT2ACTBP2PTGS1 | |
| SCHEMBL11766182 | 0.78 | TDP1 (0.35) | CNR2LIPGPTGS2TLR8 | |
| SCHEMBL11763203 | 0.74 | — | — | |
| SCHEMBL21010698 | 0.74 | TLR8 (0.31) | KMT2AMAPTTLR8NPC1RAB9A | |
| SCHEMBL8157999 | 0.74 | TP53 (0.42) | KMT2A | |
| SCHEMBL21010589 | 0.73 | PSMB5 (0.38) | KMT2ATSHR | |
| SCHEMBL8055036 | 0.73 | TSHR (0.32) | KMT2AMAPTTSHRNPC1RAB9A | |
| SCHEMBL29981544 | 0.73 | TAAR1 (0.58) | TAAR1CHRM2KMT2ACTBP2LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064288-A1 | PROCESS FOR THE PREPARATION OF BISPHOSPHINES | Ineos Acrylics UK Limited (GB) | 2001-01-03 | — | — | EP | disclosed |
| EP-1003754-A1 | METHOD OF MANUFACTURING PHOSPHINE COMPOUND | Ineos Acrylics UK Limited (GB) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999047528-A1 | PROCESS FOR THE PREPARATION OF BISPHOSPHINES | INEOS ACRYLICS UK LIMITED (GB) | 1999-09-23 | — | — | WO | disclosed |
| WO-1999009040-A1 | METHOD OF MANUFACTURING PHOSPHINE COMPOUND | INEOS ACRYLICS UK LIMITED (GB) | 1999-02-25 | — | — | WO | disclosed |