Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 5/20 | 0.46 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | MAX | P61244 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.39 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.39 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.39 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7753788 | 1.00 | P2RX1 (0.46) | P2RX1TACR1MAPTKDM4EMEN1 | |
| SCHEMBL7759728 | 0.91 | TMPRSS4 (0.43) | P2RX1MAPTKDM4ETMPRSS4HTT | |
| SCHEMBL3651343 | 0.90 | MAPT (0.50) | MAPTMEN1KMT2AFAAHTRPV1 | |
| SCHEMBL3651341 | 0.90 | MAPT (0.50) | MAPTMEN1KMT2AFAAHTRPV1 | |
| SCHEMBL13375875 | 0.88 | RAB9A (0.46) | MAPTMEN1KMT2AFAAHTRPV1 | |
| SCHEMBL2087130 | 0.81 | KMT2A (0.43) | MAPTKDM4EMEN1KMT2AP2RX7 | |
| SCHEMBL4920373 | 0.81 | KMT2A (0.43) | MAPTKDM4EMEN1KMT2AP2RX7 | |
| SCHEMBL12793870 | 0.81 | KMT2A (0.43) | MAPTKDM4EMEN1KMT2AP2RX7 | |
| SCHEMBL7758060 | 0.80 | KMT2A (0.47) | MAPTMEN1KMT2AFAAHTRPV1 | |
| SCHEMBL7758055 | 0.80 | KMT2A (0.47) | MAPTMEN1KMT2AFAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077933-A1 | SUBSTITUTED GUANIDINES AND DIAMINONITROETHENES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-02-28 | — | — | EP | disclosed |
| US-6147098-A | USEFUL IN THE TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM, CARDIOVASCULAR SYSTEM, PULMONARY SYSTEM, GASTROINTESTINAL SYSTEM AND ENDOCRINOLOGIC SYSTEM | NOVO NORDISK A/S (DK) | 2000-11-14 | — | — | US | disclosed |
| WO-1999058497-A1 | SUBSTITUTED GUANIDINES AND DIAMINONITROETHENES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1999-11-18 | — | — | WO | disclosed |