Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.39 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754013 | 1.00 | CYP2D6 (0.39) | CYP2D6CYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL7758696 | 0.80 | CDK1 (0.46) | CYP2D6CYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL17548949 | 0.80 | CDK1 (0.50) | CYP2D6CYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL8779815 | 0.76 | SKP2 (0.47) | CYP2D6CYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL2279414 | 0.75 | CDK1 (0.55) | CYP3A4ALDH1A1HSD17B10LMNAHIF1A | |
| SCHEMBL2278630 | 0.75 | CDK1 (0.55) | CYP3A4ALDH1A1HSD17B10LMNAHIF1A | |
| SCHEMBL6689622 | 0.75 | CDK1 (0.55) | CYP3A4ALDH1A1HSD17B10LMNAHIF1A | |
| SCHEMBL6691210 | 0.75 | CDK1 (0.55) | CYP3A4ALDH1A1HSD17B10LMNAHIF1A | |
| SCHEMBL6689618 | 0.75 | CDK1 (0.55) | CYP3A4ALDH1A1HSD17B10LMNAHIF1A | |
| SCHEMBL3894996 | 0.75 | CDK1 (0.55) | CYP3A4ALDH1A1HSD17B10LMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702008-B1 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS (JP) | 2001-08-29 | — | — | EP | disclosed |
| EP-1081141-A1 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2001-03-07 | — | — | EP | disclosed |
| US-5856504-A | TREATING A 2-(ALKYLTHIO)BENZALDEHYDE OXIME WITH A HALOGEN COMPOUND | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| US-5773626-A | HALOGENATION OF A 2-(ALKYLTHIO)BENZALDEHYDE OXIME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0805151-A1 | PROCESSES FOR PRODUCING ISOTHIAZOLE DERIVATIVES | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5633384-A | FROM O-ALKYLTHIOBENZONITRILES | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| EP-0702008-A2 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-03-20 | — | — | EP | disclosed |