Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490805 | 0.81 | IGF1R (0.39) | SKP2IGF1RALOX15 | |
| SCHEMBL7758696 | 0.79 | CDK1 (0.46) | SKP2HPGDNPC1MAPK1HTT | |
| SCHEMBL6231117 | 0.79 | HPGD (0.41) | SKP2HPGDNPC1MAPK1HTT | |
| SCHEMBL21706152 | 0.78 | SKP2 (0.46) | SKP2ALDH1A1HSD17B10CYP3A4ESR1 | |
| SCHEMBL26034046 | 0.78 | SKP2 (0.50) | SKP2ALDH1A1HSD17B10CYP3A4ESR1 | |
| SCHEMBL7628388 | 0.78 | MAPT (0.52) | MAPK1CA2CA1ALDH1A1HSD17B10 | |
| SCHEMBL5181634 | 0.78 | SLC6A2 (0.31) | SLC6A2SLC6A4IGF1RALOX15 | |
| SCHEMBL7628384 | 0.78 | BACE1 (0.32) | HPGDALDH1A1HSD17B10KDM4ELMNA | |
| SCHEMBL5181629 | 0.78 | MIF (0.31) | IGF1RALOX15 | |
| SCHEMBL7754011 | 0.76 | CYP2D6 (0.39) | SKP2HPGDNPC1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770599-A1 | PROCESS FOR THE PREPARATION OF AROMATIC OR HETEROAROMATIC SULFONYL HALIDES | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-05-02 | — | — | EP | disclosed |