⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5857523 | 0.82 | — | — | |
| SCHEMBL5855559 | 0.72 | — | — | |
| SCHEMBL1419 | 0.72 | — | — | |
| SCHEMBL1780973 | 0.71 | — | — | |
| SCHEMBL1782806 | 0.71 | — | — | |
| SCHEMBL6575355 | 0.68 | NOS3 (0.30) | — | |
| SCHEMBL687177 | 0.68 | NOS3 (0.30) | — | |
| SCHEMBL9808297 | 0.68 | NOS3 (0.30) | — | |
| SCHEMBL495581 | 0.68 | — | — | |
| SCHEMBL205065 | 0.68 | NOS3 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3160 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024120442-A1 | PAK4 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | CONVERGEN (SUZHOU) PHARMACEUTICAL CO., LTD. (CN) | 2024-06-13 | — | — | WO | claimed |
| US-20240190883-A1 | KRAS PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2024-06-13 | — | — | US | claimed |
| EP-3307798-B2 | ALIGNMENT COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2024-06-05 | — | — | EP | claimed |
| US-20240174643-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2024-05-30 | — | — | US | claimed |
| CN-118076602-A | Heteroaryl-acetylenes, pharmaceutical compositions thereof and their therapeutic uses | 嘉兴优博生物技术有限公司 | 2024-05-24 | — | — | CN | claimed |
| US-20240148699-A1 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-05-09 | — | — | US | claimed |
| EP-4361163-A1 | PROTEIN INHIBITOR OR DEGRADING AGENT, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND PHARMACEUTICAL USE | JING MEDICINE TECHNOLOGY (SHANGHAI) LTD. (CN) | 2024-05-01 | — | — | EP | claimed |
| WO-2024084448-A2 | FUSED BICYCLIC COMPOUNDS AND THEIR USE AS MER AND AXL INHIBITORS | DONG-A ST CO., LTD. (KR) | 2024-04-25 | — | — | WO | claimed |
| EP-4355741-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | Biotheryx, Inc. (US) | 2024-04-24 | — | — | EP | claimed |
| US-20240124418-A1 | PDE4 DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX INC (US) | 2024-04-18 | — | — | US | claimed |
| EP-0183901-A2 | Bifunctional haptens, method for their production and their use | BEHRINGWERKE Aktiengesellschaft (DE) | 1986-06-11 | — | — | EP | claimed |
| EP-0153907-A2 | Compounds containing piperidine and their use in the stabilisation of synthetic polymers | CIBA-GEIGY AG (CH) | 1985-09-04 | — | — | EP | claimed |
| US-4501837-A | LIGHT, HEAT, AND OXIDATION STABILIZERS | CIBA-GEIGY S.P.A. (IT) | 1985-02-26 | — | — | US | claimed |
| EP-0031304-B1 | PIPERIDINE DERIVATIVES AS STABILIZERS FOR SYNTHETIC POLYMERS | CIBA-GEIGY S.p.A. (IT) | 1984-06-13 | — | — | EP | claimed |
| EP-0101665-A2 | Reactive dyestuffs of the dioxazine series, their preparation and their use | CIBA-GEIGY AG (CH) | 1984-02-29 | — | — | EP | claimed |
| EP-0087564-A1 | Specific binding assay method, reagent system and labelled conjugate for use in this method | MILES LABORATORIES, INC. (US) | 1983-09-07 | — | — | EP | claimed |
| EP-0024282-B1 | BENZOYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINES | Dr. Karl Thomae GmbH (DE) | 1983-05-18 | — | — | EP | claimed |
| EP-0031304-A1 | Piperidine derivatives as stabilizers for synthetic polymers | CIBA-GEIGY S.p.A. (IT) | 1981-07-01 | — | — | EP | claimed |
| US-4108829-A | PHOTOSTABILITY | CHIMOSA CHIMICA ORGANICA S.P.A. (IT) | 1978-08-22 | — | — | US | claimed |
| US-3948891-A | INITIATORS OF VINYL POLYMERIZATION | THE DOW CHEMICAL COMPANY (US) | 1976-04-06 | — | — | US | claimed |