Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301539 | 0.94 | — | — | |
| SCHEMBL27946476 | 0.92 | — | — | |
| SCHEMBL9858502 | 0.92 | — | — | |
| SCHEMBL27759569 | 0.92 | — | — | |
| SCHEMBL27759565 | 0.92 | — | — | |
| SCHEMBL8073220 | 0.92 | — | — | |
| SCHEMBL27738878 | 0.92 | — | — | |
| Formaldehyde SCHEMBL10381232 | 0.84 | ALDH1A1 (0.43) | ALDH1A1LMNASLC15A2HPGDKDM4E | |
| Formic Acid Methyl Ester SCHEMBL17372692 | 0.82 | ALDH1A1 (0.41) | ALDH1A1LMNASLC15A2HPGDKDM4E | |
| SCHEMBL11167605 | 0.80 | HPGD (0.55) | ALDH1A1HPGDKDM4EATMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016088138-A1 | DIPHENYLOXIRANES, PROCESS FOR PREPARATION THEREOF, AND ITS USE IN AN ENANTIOSELECTIVE SYNTHESIS OF (+)-SERTRALINE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-09 | — | — | WO | disclosed |
| EP-1073645-A2 | PROCESS FOR THE PREPARATION OF TETRALONE IMINES FOR THE PREPARATION OF ACTIVE PHARMACEUTICAL COMPOUNDS | Ciba SC Holding AG (CH) | 2001-02-07 | — | — | EP | disclosed |
| US-6054614-A | Process for the preparation of tetralone imines for the preparation of active pharmaceutical compounds | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-04-25 | — | — | US | disclosed |
| WO-1999055686-A2 | PROCESS FOR THE PREPARATION OF TETRALONE IMINES FOR THE PREPARATION OF ACTIVE PHARMACEUTICAL COMPOUNDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1999-11-04 | — | — | WO | disclosed |
| EP-0346226-A1 | Process for the preparation of 4-aryl disubstituted-1-tetralones | SYNTHELABO (FR) | 1989-12-13 | — | — | EP | disclosed |