Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1A1 | P14550 | 6/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.59 |
| ▸ | PTGDR2 | Q9Y5Y4 | 14/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.48 |
| ▸ | PTGIR | P43119 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7186763 | 0.93 | AKR1B1 (0.58) | AKR1A1AKR1B1PTGDR2 | |
| SCHEMBL7951912 | 0.93 | AKR1A1 (0.60) | AKR1A1AKR1B1PTGDR2CYP2C9 | |
| SCHEMBL2098560 | 0.90 | AKR1B1 (0.58) | AKR1A1AKR1B1PTGDR2 | |
| SCHEMBL7755683 | 0.90 | AKR1A1 (0.58) | AKR1A1AKR1B1PTGDR2 | |
| SCHEMBL2098715 | 0.90 | AKR1B1 (0.70) | AKR1A1AKR1B1PTGDR2 | |
| Water SCHEMBL5501664 | 0.89 | AKR1B1 (0.69) | AKR1A1AKR1B1PTGDR2 | |
| SCHEMBL2101752 | 0.89 | AKR1B1 (0.59) | AKR1A1AKR1B1PTGDR2 | |
| SCHEMBL7517303 | 0.89 | AKR1B1 (0.61) | AKR1A1AKR1B1PTGDR2 | |
| SCHEMBL2098293 | 0.88 | AKR1B1 (0.60) | AKR1A1AKR1B1PTGDR2 | |
| SCHEMBL7751532 | 0.87 | AKR1B1 (0.58) | AKR1A1AKR1B1PTGDR2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001064205-A2 | COMPOSITIONS CONTAINING A SUBSTITUTED INDOLEALKANOIC ACID AND AN ANGIOTENSIN CONVERTING ENZYME INHIBITOR | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2001-09-07 | — | — | WO | claimed |
| WO-2001051489-A2 | METHODS FOR LOWERING URIC ACID LEVELS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2001-07-19 | — | — | WO | claimed |
| WO-2001064205-A2 | COMPOSITIONS CONTAINING A SUBSTITUTED INDOLEALKANOIC ACID AND AN ANGIOTENSIN CONVERTING ENZYME INHIBITOR | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2001-09-07 | — | — | WO | disclosed |