Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | CASP3 | P42574 | 3/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.58 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.58 |
| ▸ | DPP4 | P27487 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15524969 | 0.88 | TDP1 (0.77) | NPC1RAB9ACASP3SENP7SENP6 | |
| SCHEMBL30572 | 0.88 | TDP1 (0.77) | NPC1RAB9ACASP3SENP7SENP6 | |
| SCHEMBL28251466 | 0.88 | TDP1 (0.77) | NPC1RAB9ACASP3SENP7SENP6 | |
| Hydrochloric Acid SCHEMBL27556767 | 0.86 | TDP1 (0.74) | NPC1RAB9ACASP3SENP7SENP6 | |
| SCHEMBL12065203 | 0.85 | NPC1 (0.68) | NPC1RAB9ACASP3SENP7SENP6 | |
| SCHEMBL28013318 | 0.85 | L3MBTL1 (0.72) | NPC1RAB9ACASP3SENP7SENP6 | |
| SCHEMBL24599291 | 0.85 | FFAR1 (0.69) | NPC1RAB9ACASP3SENP7SENP6 | |
| SCHEMBL4217497 | 0.85 | DPP4 (0.77) | NPC1RAB9ACASP3SENP7SENP6 | |
| SCHEMBL1985867 | 0.85 | NPC1 (0.62) | NPC1RAB9ACASP3SENP7SENP6 | |
| SCHEMBL12918716 | 0.85 | NR4A2 (0.70) | NPC1RAB9ACASP3SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811595-B1 | HYDROCHALCONE DERIVATIVES, COMESTIC COMPOSITIONS CONTAINING THE SAME, AND PROCESSES FOR THE PREPARATION OF BOTH | MITSUI CHEMICALS INC (JP) | 2001-02-07 | — | — | EP | disclosed |
| US-5880314-A | DEPIGMENTING; SAFE TO SKIN, STORAGE STABLE | MITSUI CHEMICALS, INC. (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0811595-A1 | HYDROCHALCONE DERIVATIVES, COMESTIC COMPOSITIONS CONTAINING THE SAME, AND PROCESSES FOR THE PREPARATION OF BOTH | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-12-10 | — | — | EP | disclosed |