Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL4051043 | 0.81 | AKR1C3 (0.53) | AKR1C3HTTKDM4EALDH1A1TSHR | |
| SCHEMBL2831497 | 0.74 | AKR1C3 (0.47) | AKR1C3HTTKDM4ECYP2C9APEX1 | |
| Styrene SCHEMBL1628243 | 0.72 | AKR1C3 (0.81) | AKR1C3HTTALDH1A1TSHRDHODH | |
| SCHEMBL28588058 | 0.72 | AKR1C3 (0.57) | AKR1C3HTTKDM4EALDH1A1CYP2C9 | |
| SCHEMBL14040079 | 0.72 | AKR1C3 (0.57) | AKR1C3HTTKDM4EALDH1A1CYP2C9 | |
| SCHEMBL8746657 | 0.72 | AKR1C3 (0.55) | AKR1C3HTTKDM4ECYP2C9APEX1 | |
| SCHEMBL8746654 | 0.72 | AKR1C3 (0.55) | AKR1C3HTTKDM4ECYP2C9APEX1 | |
| Styrene SCHEMBL11433472 | 0.71 | AKR1C3 (0.52) | AKR1C3HTTKDM4EALDH1A1TSHR | |
| Styrene SCHEMBL22399380 | 0.71 | AKR1C3 (0.52) | AKR1C3HTTKDM4EALDH1A1TSHR | |
| Styrene SCHEMBL9067618 | 0.70 | HTT (0.59) | AKR1C3HTTKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150847-A1 | METHOD FOR MAKING A WRITING OR COLOURING PENCIL BY TRIPLE EXTRUSION AND WRITING OR COLOURING PENCIL COMPRISING AN INTERMEDIATE PROTECTIVE LAYER | CONTE S.A. (FR) | 2001-11-07 | — | — | EP | disclosed |
| WO-2001043987-A1 | METHOD FOR MAKING A WRITING OR COLOURING PENCIL BY TRIPLE EXTRUSION AND WRITING OR COLOURING PENCIL COMPRISING AN INTERMEDIATE PROTECTIVE LAYER | CONTE (FR) | 2001-06-21 | — | — | WO | disclosed |
| EP-0505262-B1 | Method of manufacturing a crayon or pencil by triple extrusion, crayon or pencil featuring an intermediate protective jacket for the lead | CONTE SA (FR) | 1993-11-18 | — | — | EP | disclosed |