SCHEMBL2831497

SCHEMBL2831497

C=Cc1cccc(C=C(C)C(=O)O)c1C=C

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ AKR1C3 P42330 1/20 0.47
▸ KDM4E B2RXH2 2/20 0.40
▸ APEX1 P27695 9/20 0.37
▸ HTT P42858 1/20 0.37
▸ CYP2C9 P11712 1/20 0.35
▸ RXRA P19793 1/20 0.34
▸ RXRB P28702 1/20 0.34
▸ NR4A2 P43354 1/20 0.34
▸ RXRG P48443 1/20 0.34
▸ PARP1 P09874 1/20 0.33
▸ PARP15 Q460N3 1/20 0.33
▸ PARP10 Q53GL7 1/20 0.33
▸ SLC9A1 P19634 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL1562495 0.95 AKR1C3 (0.43) AKR1C3KDM4EAPEX1HTTCYP2C9
Styrene SCHEMBL4051043 0.92 AKR1C3 (0.53) AKR1C3KDM4EAPEX1HTTCYP2C9
SCHEMBL5885336 0.89 AKR1C3 (0.38) AKR1C3KDM4EAPEX1HTT
SCHEMBL2451012 0.87 ALDH1A1 (0.40) AKR1C3KDM4EAPEX1CYP2C9SLC9A1
SCHEMBL14993955 0.86 AKR1C3 (0.43) AKR1C3KDM4EAPEX1HTTCYP2C9
SCHEMBL3808317 0.84 AKR1C3 (0.44) AKR1C3KDM4EAPEX1HTTMAPT
Methacrylic Acid SCHEMBL28827024 0.84 KDM4E (0.36) AKR1C3KDM4EHTTSLC9A1MAPT
SCHEMBL14040079 0.84 AKR1C3 (0.57) AKR1C3KDM4EAPEX1HTTCYP2C9
SCHEMBL28588058 0.84 AKR1C3 (0.57) AKR1C3KDM4EAPEX1HTTCYP2C9
SCHEMBL8746654 0.83 AKR1C3 (0.55) AKR1C3KDM4EAPEX1HTTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118459648-A Preparation method of hydrophilic polymer microsphere with controllable particle size 武汉华大智造科技有限公司 2024-08-09 — — CN claimed
CN-111375360-B Preparation method of magnetic microspheres with uniform particle size 苏州海狸生物医学工程有限公司 2022-03-04 — — CN claimed
CN-111375360-A Preparation method of magnetic microspheres with uniform particle size 苏州海狸生物医学工程有限公司 2020-07-07 — — CN claimed
EP-0938318-B1 TABLET WITH CONTROLLED RELEASE OF ALFUZOSINE CHLORYDRATE SANOFI SYNTHELABO (FR) 2001-05-02 — — EP claimed
CN-119972020-A Method for preparing magnetic polymer microsphere 东南大学 2025-05-13 — — CN disclosed
CN-118459648-A Preparation method of hydrophilic polymer microsphere with controllable particle size 武汉华大智造科技有限公司 2024-08-09 — — CN disclosed
US-20240252480-A1 DOSAGE FORM FOR NICOTINE REPLACEMENT THERAPY HALEON US HOLDINGS LLC 2024-08-01 — — US disclosed
CN-118098746-A Porous magnetic polymer microsphere and preparation method thereof 东南大学 2024-05-28 — — CN disclosed
CN-117979952-A Dosage form for nicotine replacement therapy 葛兰素史克消费保健(美国)控股有限责任公司 2024-05-03 — — CN disclosed
EP-4346764-A1 DOSAGE FORM FOR NICOTINE REPLACEMENT THERAPY GlaxoSmithKline Consumer Healthcare Holdings (US) LLC (US) 2024-04-10 — — EP disclosed
EP-3191590-B1 SORBENT MATERIAL FOR SEPARATING BIO-MACROMOLECULES QUANTUMDX GROUP LTD (GB) 2024-02-21 — — EP disclosed
CN-117339583-A Cuttlefish bone derived material and preparation method and application thereof 昆明理工大学 2024-01-05 — — CN disclosed
EP-0938318-B1 TABLET WITH CONTROLLED RELEASE OF ALFUZOSINE CHLORYDRATE SANOFI SYNTHELABO (FR) 2001-05-02 — — EP disclosed
US-5880240-A POLYMER PREPARED BY POLYMERIZING MIXTURE OF DIVINYLBENZENE, MONOMER SELECTED FROM STYRENE, METHYLSTYRENE AND ETHYLVINYLBENZENE, AND VINYLBENZYLOXYALKANE DERIVATIVE ARAKAWA CHEMICAL INDUSTRIES, LTD. (JP) 1999-03-09 — — US disclosed
EP-0831113-A1 ALKYLATED POROUS RESIN, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF ARAKAWA CHEMICAL INDUSTRIES, LTD. (JP) 1998-03-25 — — EP disclosed
US-5731395-A POLYMER CONTAINING DIVINYLBENZENE AND STYRENE COMPOUND ARAKAWA CHEMICAL INDUSTRIES, LTD. (JP) 1998-03-24 — — US disclosed
EP-0764667-A1 FUNCTION-CONTAINING POROUS RESIN AND PROCESS FOR THE PRODUCTION THEREOF ARAKAWA CHEMICAL INDUSTRIES, LTD. (JP) 1997-03-26 — — EP disclosed
EP-0022533-B2 PROCESS FOR THE PREPARATION OF POLYVALENT PHENOLS BAYER AG (DE) 1986-04-02 — — EP disclosed
EP-0022533-B1 PROCESS FOR THE PREPARATION OF POLYVALENT PHENOLS BAYER AG (DE) 1982-07-28 — — EP disclosed
EP-0022533-A1 Process for the preparation of polyvalent phenols BAYER AG (DE) 1981-01-21 — — EP disclosed
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