SCHEMBL7755202

SCHEMBL7755202

Cc1cc(-n2nc3ccccc3n2)ccc1-c1ccccc1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 10/20 0.47
NPC1 O15118 9/20 0.47
MEN1 O00255 5/20 0.47
KMT2A Q03164 5/20 0.47
LMNA P02545 3/20 0.45
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
HPGD P15428 7/20 0.42
KDM4E B2RXH2 6/20 0.42
HTT P42858 1/20 0.41
ATM Q13315 2/20 0.40
MAPT P10636 5/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
TSHR P16473 3/20 0.39
NFKB1 P19838 2/20 0.39
NFKB2 Q00653 2/20 0.39
RELA Q04206 2/20 0.39
USP2 O75604 2/20 0.39
ALOX15 P16050 1/20 0.39
ALDH1A1 P00352 5/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29481329 0.82 NPC1 (0.56) RAB9ANPC1MEN1KMT2ALMNA
SCHEMBL294530 0.82 NPC1 (0.56) RAB9ANPC1MEN1KMT2ALMNA
SCHEMBL14324607 0.81 PPARG (0.49) RAB9ANPC1MEN1KMT2APPARG
SCHEMBL9813570 0.79 NPC1 (0.51) RAB9ANPC1MEN1KMT2ALMNA
SCHEMBL3221400 0.77 NPC1 (0.67) RAB9ANPC1MEN1KMT2ALMNA
SCHEMBL7755194 0.76 NPC1 (0.69) RAB9ANPC1MEN1KMT2ALMNA
SCHEMBL11469488 0.75 PPARG (0.54) RAB9ANPC1MEN1KMT2ALMNA
SCHEMBL31713129 0.72 NPC1 (0.42) RAB9ANPC1MEN1KMT2ALMNA
SCHEMBL1828915 0.71 TP53 (0.52) RAB9ANPC1MEN1KMT2ALMNA
SCHEMBL29362536 0.71 TP53 (0.52) RAB9ANPC1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0767074-B1 A thermal recording medium JUJO PAPER CO LTD (JP) 2001-04-11 EP disclosed
EP-0767074-A2 A thermal recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-04-09 EP disclosed