SCHEMBL11469488

SCHEMBL11469488

Cc1cc(-n2nc3ccccc3n2)cc(C)c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.54
PPARA Q07869 1/20 0.54
KDM4E B2RXH2 5/20 0.52
HPGD P15428 4/20 0.52
NPC1 O15118 9/20 0.50
RAB9A P51151 9/20 0.50
LMNA P02545 2/20 0.50
HTT P42858 2/20 0.46
POLB P06746 1/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
ALDH1A1 P00352 6/20 0.41
MAPT P10636 3/20 0.41
TTR P02766 2/20 0.41
STAT1 P42224 1/20 0.41
ALOX5 P09917 1/20 0.40
PTGS1 P23219 1/20 0.40
PTGS2 P35354 1/20 0.40
SMN1; SMN2 Q16637 4/20 0.39
GAA P10253 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2549815 0.85 PPARG (0.52) PPARGPPARAKDM4EHPGDNPC1
SCHEMBL11468683 0.84 RAB9A (0.50) PPARGPPARAKDM4EHPGDNPC1
SCHEMBL29481329 0.81 NPC1 (0.56) PPARGPPARAKDM4EHPGDNPC1
SCHEMBL294530 0.81 NPC1 (0.56) PPARGPPARAKDM4EHPGDNPC1
SCHEMBL11459762 0.81 NPC1 (0.49) PPARGPPARAKDM4EHPGDNPC1
SCHEMBL6157945 0.79 PPARG (0.41) PPARGPPARAKDM4EHPGDNPC1
SCHEMBL3221400 0.78 NPC1 (0.67) PPARGPPARAKDM4EHPGDNPC1
SCHEMBL14462710 0.78 PPARG (0.58) PPARGPPARAKDM4EHPGDNPC1
SCHEMBL9813570 0.78 NPC1 (0.51) PPARGPPARAKDM4EHPGDNPC1
SCHEMBL7649625 0.78 NPC1 (0.51) PPARGPPARAKDM4EHPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7244776-B2 Ultraviolet light absorbers CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-07-17 US disclosed
US-20070100031-A1 Ultraviolet light absorbers RAVICHANDRAN RAMANATHAN 2007-05-03 US disclosed
US-20070100031-A1 Ultraviolet light absorbers RAVICHANDRAN RAMANATHAN 2007-05-03 US disclosed
US-7173128-B2 Ultraviolet light absorbers CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-02-06 US disclosed
US-4235999-A Bichromophoric benzotriazole-styrene ester ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1980-11-25 US disclosed
US-4187229-A Bis-benzotriazole compounds EASTMAN KODAK COMPANY (US) 1980-02-05 US disclosed
US-4174321-A POLYMERIC MOLDING MATERIALS EASTMAN KODAK COMPANY (US) 1979-11-13 US disclosed
US-4159270-A Bichromophoric benzotriazole-styrene ultraviolet stabilizers EASTMAN KODAK COMPANY (US) 1979-06-26 US disclosed
US-4127501-A BENZOXAZOLE, BENZOTHIAZOLE, BENZIMIDAZOLE, BENZOTRIAZOLE OR INDOLE DERIVATIVES EASTMAN KODAK COMPANY (US) 1978-11-28 US disclosed
US-4085089-A Benzotriazole ultraviolet stabilizing compounds and their use in organic compositions EASTMAN KODAK COMPANY (US) 1978-04-18 US disclosed
US-4073745-A Multichromophoric benzotriazole ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1978-02-14 US disclosed
US-4070337-A Bichromophoric benzotriazole-styrene ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1978-01-24 US disclosed
US-4070339-A Bichromophoric benzotriazole-styrene ester ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1978-01-24 US disclosed
US-3981884-A POLYMERS EASTMAN KODAK COMPANY (US) 1976-09-21 US disclosed