SCHEMBL7755274

SCHEMBL7755274

CN(C(N)=O)C(=O)CC#N

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 4/20 0.48
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
DPP4 P27487 2/20 0.33
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL333490 0.75
SCHEMBL1032820 0.74 MCL1 (0.50) MCL1KDM4EMAPT
SCHEMBL28504677 0.74 MCL1 (0.44) MCL1KDM4EMEN1LMNAMAPT
SCHEMBL9362533 0.73 MCL1 (0.48) MCL1KDM4EMEN1LMNAMAPT
SCHEMBL11351147 0.72 MEN1 (0.44) MCL1MEN1LMNAKMT2A
SCHEMBL28850955 0.70
SCHEMBL27290461 0.70
SCHEMBL9653268 0.70
Bromide SCHEMBL27567305 0.69 ALOX15 (0.31)
SCHEMBL15492524 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039294-B Preparation method of 3, 7-dimethyl xanthine 石药创新制药股份有限公司 2025-03-11 CN claimed
CN-119039294-A Preparation method of 3, 7-dimethyl xanthine 石药创新制药股份有限公司 2024-11-29 CN claimed
CN-112142738-A Preparation method of theobromine 石药集团新诺威制药股份有限公司 2020-12-29 CN claimed
CN-119039294-B Preparation method of 3, 7-dimethyl xanthine 石药创新制药股份有限公司 2025-03-11 CN disclosed
CN-119039294-A Preparation method of 3, 7-dimethyl xanthine 石药创新制药股份有限公司 2024-11-29 CN disclosed
CN-114213342-A Production system and method for preparing 6-amino-1,3-dimethyl uracil 青岛科技大学 2022-03-22 CN disclosed
CN-114213342-A Production system and method for preparing 6-amino-1,3-dimethyl uracil 青岛科技大学 2022-03-22 CN disclosed
CN-112142738-A Preparation method of theobromine 石药集团新诺威制药股份有限公司 2020-12-29 CN disclosed
CN-112142738-A Preparation method of theobromine 石药集团新诺威制药股份有限公司 2020-12-29 CN disclosed
CN-102329317-B Method for synthesizing theobromine SHIJIAZHUANG PHARMACEUTICAL INVOVATION CO LTD 2013-06-05 CN disclosed
JP-2001151761-A METHOD FOR PRODUCING URACIL OF THYMINE MITSUI CHEMICALS INC 2001-06-05 JP disclosed