SCHEMBL7755345

SCHEMBL7755345

CCCCCOC=CCCC[O]

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 3/20 0.38
FAAH O00519 2/20 0.38
TRPV1 Q8NER1 1/20 0.38
LPAR1 Q92633 2/20 0.37
LPAR2 Q9HBW0 2/20 0.37
EPHX2 P34913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7756607 0.98 FAAH (0.41) LPAR3FAAHTRPV1LPAR1LPAR2
SCHEMBL7754323 0.94 LPAR3 (0.35) LPAR3FAAHTRPV1LPAR1LPAR2
SCHEMBL7770457 0.90 FAAH (0.45) LPAR3FAAHTRPV1
SCHEMBL7755103 0.90 LPAR3 (0.35) LPAR3FAAHTRPV1LPAR1LPAR2
SCHEMBL7756673 0.88 FAAH (0.38) LPAR3FAAHTRPV1LPAR1LPAR2
SCHEMBL7753966 0.88 LPAR3 (0.32) LPAR3FAAHTRPV1LPAR1LPAR2
SCHEMBL23501872 0.87 LPAR3 (0.41) LPAR3TRPV1LPAR1LPAR2
SCHEMBL23501869 0.87 LPAR3 (0.41) LPAR3TRPV1LPAR1LPAR2
SCHEMBL25228930 0.85 LPAR2 (0.48) LPAR3FAAHTRPV1LPAR1LPAR2
SCHEMBL25272319 0.85 LPAR2 (0.48) LPAR3FAAHTRPV1LPAR1LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0835248-B1 1-AMINO-3-BENZYLURACILS BASF AG (DE) 2001-02-21 EP disclosed
CN-1189824-A 1-amino-3-benzyluracils BASF AG (DE) 1998-08-05 CN disclosed
EP-0835248-A1 1-AMINO-3-BENZYLURACILS BASF AKTIENGESELLSCHAFT (DE) 1998-04-15 EP disclosed
WO-1997001543-A1 1-AMINO-3-BENZYLURACILS BASF AKTIENGESELLSCHAFT (DE) 1997-01-16 WO disclosed