Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 15/20 | 0.54 |
| ▸ | NR1H3 | Q13133 | 15/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001280 | 0.93 | NR1H2 (0.48) | NR1H2NR1H3ARNR1I2MEN1 | |
| SCHEMBL21519640 | 0.93 | NR1H2 (0.48) | NR1H2NR1H3ARNR1I2MEN1 | |
| SCHEMBL3983038 | 0.93 | NR1H2 (0.48) | NR1H2NR1H3ARNR1I2MEN1 | |
| SCHEMBL12069742 | 0.90 | NR1H2 (0.47) | NR1H2NR1H3ARNR1I2CYP3A4 | |
| SCHEMBL19503409 | 0.90 | NR1H2 (0.46) | NR1H2NR1H3ARNR1I2MEN1 | |
| SCHEMBL5073885 | 0.88 | RORC (0.47) | NR1H2NR1H3ARCYP3A4MAPK1 | |
| SCHEMBL30306604 | 0.84 | NR1H2 (0.43) | NR1H2NR1H3ARNR1I2MLYCD | |
| SCHEMBL7153351 | 0.83 | EGFR (0.50) | NR1H2NR1H3ARCYP3A4MAPT | |
| SCHEMBL15362902 | 0.83 | MAPT (0.51) | NR1H2NR1H3ARNR1I2MAPT | |
| SCHEMBL5283357 | 0.82 | NR1H2 (0.47) | NR1H2NR1H3ARNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846676-B1 | Process for the preparation of aromatic amines from aryl chlorides | AXIVA GMBH (DE) | 2001-02-07 | — | — | EP | disclosed |
| US-5831128-A | Synthesis of aromatic amines from chloroamatics | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |
| EP-0846676-A1 | Process for the preparation of aromatic amines from aryl chlorides | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-10 | — | — | EP | disclosed |