SCHEMBL7755552

SCHEMBL7755552

Nc1cc(OS(=O)(=O)O)ccc1OS(=O)(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.44
GAA P10253 1/20 0.44
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
KMT2A Q03164 2/20 0.41
THRB P10828 1/20 0.41
F10 P00742 3/20 0.39
CISD1 Q9NZ45 1/20 0.38
CA5A P35218 1/20 0.37
CA2 P00918 4/20 0.37
CA1 P00915 3/20 0.37
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37
MMP8 P22894 1/20 0.37
MMP13 P45452 1/20 0.37
CA9 Q16790 3/20 0.35
SLC22A6 Q4U2R8 1/20 0.35
F2 P00734 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11489743 0.87 ALDH1A1 (0.59) GLAGAAALDH1A1MEN1MAPT
SCHEMBL11028747 0.85 GAA (0.47) GLAGAAALDH1A1MEN1MAPT
SCHEMBL10900544 0.84 NR4A1 (0.52) GLAGAAALDH1A1MEN1MAPT
SCHEMBL11136116 0.82 GAA (0.45) GLAGAAALDH1A1MEN1MAPT
SCHEMBL5691182 0.82 ALDH1A1 (0.46) GAAALDH1A1MEN1MAPTKMT2A
SCHEMBL6326972 0.82 GAA (0.50) GLAGAAALDH1A1MEN1MAPT
SCHEMBL17469926 0.82 GLA (0.47) GLAGAAALDH1A1F10CISD1
SCHEMBL7766505 0.81 CISD1 (0.41) GAAALDH1A1MAPTCISD1CA5A
SCHEMBL10448617 0.81 ALDH1A1 (0.53) GLAGAAALDH1A1MEN1MAPT
SCHEMBL5066593 0.79 ALDH1A1 (0.55) ALDH1A1THRBCA5ACA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0323399-B1 OPTICAL BRIGHTENER DISPERSION CIBA-GEIGY AG (CH) 1993-02-17 EP claimed
EP-0323399-A1 Optical brightener dispersion CIBA-GEIGY AG (CH) 1989-07-05 EP claimed
EP-0122423-B1 DISAZO REACTIVE DYESTUFFS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE DYEING OR PRINTING OF SUBSTRATES BAYER AG (DE) 1987-07-08 EP claimed
EP-0669380-B1 Process for the preparation of azo dyes CIBA SC HOLDING AG (CH) 2001-03-28 EP disclosed
EP-0669380-A2 Process for the preparation of azo dyes CIBA-GEIGY AG (CH) 1995-08-30 EP disclosed
EP-0323399-B1 OPTICAL BRIGHTENER DISPERSION CIBA-GEIGY AG (CH) 1993-02-17 EP disclosed
EP-0323399-A1 Optical brightener dispersion CIBA-GEIGY AG (CH) 1989-07-05 EP disclosed
EP-0122423-B1 DISAZO REACTIVE DYESTUFFS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE DYEING OR PRINTING OF SUBSTRATES BAYER AG (DE) 1987-07-08 EP disclosed
EP-0066714-A2 Reactive dyestuffs BASF Aktiengesellschaft (DE) 1982-12-15 EP disclosed
EP-0061625-A2 Reactive dyestuffs BASF Aktiengesellschaft (DE) 1982-10-06 EP disclosed
EP-0014378-B1 TRIS- OR TETRAKISAZO-DYESTUFFS AND THEIR USE FOR DYEING LEATHER BASF Aktiengesellschaft (DE) 1981-11-04 EP disclosed
EP-0014378-A1 Tris- or tetrakisazo-dyestuffs and their use for dyeing leather BASF Aktiengesellschaft (DE) 1980-08-20 EP disclosed