Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22411194 | 0.98 | — | — | |
| Fluoride SCHEMBL28439244 | 0.96 | TSHR (0.31) | TSHRTHRB | |
| Iodide SCHEMBL29913225 | 0.96 | TSHR (0.31) | TSHRTHRB | |
| Bromide SCHEMBL3192843 | 0.96 | TSHR (0.31) | TSHRTHRB | |
| Iodide SCHEMBL1227461 | 0.96 | TSHR (0.31) | TSHRTHRB | |
| Fluoride SCHEMBL28438447 | 0.94 | — | — | |
| SCHEMBL28709976 | 0.91 | — | — | |
| SCHEMBL28608882 | 0.89 | — | — | |
| Bromide SCHEMBL14485290 | 0.88 | — | — | |
| Iodide SCHEMBL412001 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332027-B1 | Method for preparing a modified starch having improved emulsification properties | NAT STARCH CHEM CORP (US) | 2001-02-07 | — | — | EP | disclosed |
| US-5185176-A | Storage stability, resistance to oiling and gelling | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1993-02-09 | — | — | US | disclosed |
| US-4977252-A | Produced by enzymatic degradation of 1,4-alpha-D-glucosidic linkages from non-reducing ends of molecule | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1990-12-11 | — | — | US | disclosed |
| EP-0332027-A1 | Modified starch emulsifier characterized by shelf stability | National Starch and Chemical Corporation (US) | 1989-09-13 | — | — | EP | disclosed |