Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 6/20 | 0.49 |
| ▸ | CNR1 | P21554 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754630 | 1.00 | KMT2A (0.54) | KMT2AMEN1ALDH1A1TSHRHTR1A | |
| SCHEMBL7751086 | 1.00 | KMT2A (0.54) | KMT2AMEN1ALDH1A1TSHRHTR1A | |
| SCHEMBL7751114 | 1.00 | KMT2A (0.54) | KMT2AMEN1ALDH1A1TSHRHTR1A | |
| SCHEMBL7755696 | 0.90 | KMT2A (0.48) | KMT2AMEN1ALDH1A1TSHRHTR1A | |
| SCHEMBL7754579 | 0.86 | CNR2 (0.61) | KMT2AMEN1TSHRCNR2CNR1 | |
| SCHEMBL7755667 | 0.86 | CNR2 (0.61) | KMT2AMEN1TSHRCNR2CNR1 | |
| SCHEMBL7751126 | 0.86 | CNR2 (0.61) | KMT2AMEN1TSHRCNR2CNR1 | |
| SCHEMBL7755450 | 0.86 | CNR2 (0.61) | KMT2AMEN1TSHRCNR2CNR1 | |
| SCHEMBL24372296 | 0.86 | HTR1A (0.53) | KMT2AMEN1ALDH1A1TSHRHTR1A | |
| SCHEMBL3954838 | 0.83 | CNR2 (0.64) | KMT2AMEN1TSHRCNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811595-B1 | HYDROCHALCONE DERIVATIVES, COMESTIC COMPOSITIONS CONTAINING THE SAME, AND PROCESSES FOR THE PREPARATION OF BOTH | MITSUI CHEMICALS INC (JP) | 2001-02-07 | — | — | EP | disclosed |
| US-5880314-A | DEPIGMENTING; SAFE TO SKIN, STORAGE STABLE | MITSUI CHEMICALS, INC. (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0811595-A1 | HYDROCHALCONE DERIVATIVES, COMESTIC COMPOSITIONS CONTAINING THE SAME, AND PROCESSES FOR THE PREPARATION OF BOTH | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-12-10 | — | — | EP | disclosed |