Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 3/20 | 0.36 |
| ▸ | RXRB | P28702 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | RXRG | P48443 | 3/20 | 0.36 |
| ▸ | RARA | P10276 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | FABP2 | P12104 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789312 | 0.75 | SOAT1 (0.49) | RARBTSHR | |
| SCHEMBL4603480 | 0.69 | BACE1 (0.42) | ALOX5APFEN1MAPK1PTGS1MEN1 | |
| SCHEMBL3833453 | 0.69 | BACE1 (0.40) | PTGS1MEN1PTGS2KMT2AFABP2 | |
| SCHEMBL8453893 | 0.68 | SCN9A (0.44) | RARBRXRARXRBPPARGRXRG | |
| SCHEMBL14954600 | 0.67 | LMNA (0.56) | PTGS1LMNA | |
| SCHEMBL9229780 | 0.67 | LMNA (0.56) | PTGS1LMNA | |
| SCHEMBL28789939 | 0.67 | BACE1 (0.37) | ALOX5APFEN1PTGS1MEN1PTGS2 | |
| Methylene Chloride SCHEMBL27625980 | 0.67 | BACE1 (0.37) | ALOX5APFEN1PTGS1MEN1PTGS2 | |
| Pyrimidine SCHEMBL28375971 | 0.67 | ALOX5AP (0.40) | ALOX5APFEN1HPGDDHODH | |
| SCHEMBL25221380 | 0.66 | BACE1 (0.39) | ALOX5APFEN1MAPK1RAB9APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718387-B1 | A liquid crystal composition and a liquid crystal display element which contains it | SHINETSU CHEMICAL CO (JP) | 2001-03-14 | — | — | EP | disclosed |
| EP-0718387-A1 | A liquid crystal composition and a liquid crystal display element which contains it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |