Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 4/20 | 0.48 |
| ▸ | TMPRSS11D | O60235 | 6/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | MC3R | P41968 | 1/20 | 0.40 |
| ▸ | MC1R | Q01726 | 1/20 | 0.40 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 1/20 | 0.38 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6836788 | 0.89 | TLR2 (0.51) | TLR2TMPRSS11DEPHX2F2F10 | |
| SCHEMBL27473103 | 0.89 | TLR2 (0.51) | TLR2TMPRSS11DEPHX2F2F10 | |
| SCHEMBL30396736 | 0.88 | TLR2 (0.51) | TLR2TMPRSS11DMC4RMC3RMC1R | |
| SCHEMBL9161634 | 0.88 | TLR2 (0.54) | TLR2TMPRSS11DMC4RMC3RMC1R | |
| SCHEMBL3442919 | 0.88 | TLR2 (0.54) | TLR2TMPRSS11DMC4RMC3RMC1R | |
| SCHEMBL10520803 | 0.79 | MME (0.44) | TLR2TMPRSS11D | |
| SCHEMBL28896050 | 0.78 | MC4R (0.60) | TLR2MC4RMC3RMC1R | |
| SCHEMBL27117113 | 0.78 | TLR2 (0.48) | TLR2NPY1R | |
| SCHEMBL1345114 | 0.77 | CA1 (0.43) | ITGB3ITGAVNPY1RNPY4R | |
| SCHEMBL8120405 | 0.77 | HTT (0.56) | TMPRSS11D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086136-A1 | MONOCLONAL ANTIBODIES SPECIFIC FOR GUANIDINO GROUP-DERIVED ADVANCED GLYCOSYLATION ENDPRODUCTS IN BIOLOGICAL SAMPLES | ALTEON, INC. (US) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999064463-A1 | MONOCLONAL ANTIBODIES SPECIFIC FOR GUANIDINO GROUP-DERIVED ADVANCED GLYCOSYLATION ENDPRODUCTS IN BIOLOGICAL SAMPLES | ALTEON INC. (US) | 1999-12-16 | — | — | WO | disclosed |