Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 6/20 | 0.51 |
| ▸ | PPID | Q08752 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | TMPRSS11D | O60235 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27473103 | 1.00 | TLR2 (0.51) | TLR2PPIDEPHX2PPARGTMPRSS11D | |
| SCHEMBL7755924 | 0.89 | TLR2 (0.48) | TLR2EPHX2TMPRSS11DTMPRSS2F2 | |
| SCHEMBL6246298 | 0.85 | TLR2 (0.37) | TLR2F10SMN1; SMN2TSHR | |
| SCHEMBL30396736 | 0.85 | TLR2 (0.51) | TLR2EPHX2TMPRSS11DF2F10 | |
| SCHEMBL3442919 | 0.85 | TLR2 (0.54) | TLR2EPHX2TMPRSS11DF2F10 | |
| SCHEMBL9161634 | 0.85 | TLR2 (0.54) | TLR2EPHX2TMPRSS11DF2F10 | |
| SCHEMBL27834371 | 0.83 | ALDH1A1 (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4212973 | 0.83 | ALDH1A1 (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL80453 | 0.81 | BCHE (0.47) | SMN1; SMN2 | |
| SCHEMBL562113 | 0.81 | BCHE (0.47) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794875-B1 | MODIFIED ENTEROKINASE LIGHT CHAIN | NOVO NORDISK AS (DK) | 2020-07-22 | — | — | EP | disclosed |
| US-9611466-B2 | Modified enterokinase light chain | NOVO NORDISK A/S (DE) | 2017-04-04 | — | — | US | disclosed |
| US-20150064744-A1 | MODIFIED ENTEROKINASE LIGHT CHAIN | NOVO NORDISK A/S (DK) | 2015-03-05 | — | — | US | disclosed |
| CN-1177933-C | Chrysosporium cellulase and methods of use thereof | ��ˡ����ס���������� | 2004-12-01 | — | — | CN | disclosed |
| US-6746859-B1 | A RECOMBINANT, BIOLOGICALLY ACTIVE, ENTEROKINASE LIGHT CHAIN, FREE OF ENTEROKINASE HEAVY CHAIN | GENETICS INSTITUTE, LLC | 2004-06-08 | — | — | US | disclosed |
| EP-0679189-B1 | Cloning of enterokinase and method of use | INST GENETICS LLC (US) | 2003-06-04 | — | — | EP | disclosed |
| US-5665566-A | Cloning of enterokinase and method of use | GENETICS INSTITUTE, INC. (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0679189-A1 | CLONING OF ENTEROKINASE AND METHOD OF USE | GENETICS INSTITUTE, INC. (US) | 1995-11-02 | — | — | EP | disclosed |
| WO-1994016083-A1 | CLONING OF ENTEROKINASE AND METHOD OF USE | GENETICS INSTITUTE, INC. (US) | 1994-07-21 | — | — | WO | disclosed |
| US-4705875-A | Substituted fructose compounds and vitamin supplements and methods for making same | BANK OF AMERICA NATIONAL TRUST AND SAVINGS ASSOCIATION | 1987-11-10 | — | — | US | disclosed |
| US-4588717-A | FATTY ACID ESTERS OF PHYTOSTEROLS | DAVID C. MITCHELL MEDICAL RESEARCH INSTITUTE (US) | 1986-05-13 | — | — | US | disclosed |
| US-4048416-A | ION EXCHANGE RESINS | EXPLOATERINGS AKTIEBOLAGET T.B.F. (SW) | 1977-09-13 | — | — | US | disclosed |