SCHEMBL7756008

SCHEMBL7756008

C[SiH](C)[Ti](Cc1ccccc1)(Cc1ccccc1)(c1cccc2c1Cc1ccccc1-2)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.42
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 3/20 0.33
APAF1 O14727 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
HTR7 P34969 1/20 0.33
HTR2B P41595 1/20 0.33
MEN1 O00255 1/20 0.33
HPGD P15428 1/20 0.33
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32
DRD3 P35462 1/20 0.32
PGR P06401 1/20 0.32
GAA P10253 1/20 0.31
CASP1 P29466 1/20 0.31
BLM P54132 1/20 0.31
CASP7 P55210 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7934541 0.87 PNMT (0.35) PNMTRAB9ANPC1
SCHEMBL797008 0.81 PNMT (0.40) PNMTRAB9ANPC1HTR7HTR2B
SCHEMBL7756049 0.78 PNMT (0.45) PNMTRAB9ANPC1ALDH1A1APAF1
SCHEMBL7607477 0.77 PNMT (0.47) PNMTRAB9ANPC1ALDH1A1MAPT
SCHEMBL7755358 0.77 PNMT (0.42) PNMTRAB9ANPC1ALDH1A1APAF1
SCHEMBL8373278 0.77 PNMT (0.42) PNMTRAB9ANPC1ALDH1A1APAF1
SCHEMBL7201387 0.76 PNMT (0.42) PNMTRAB9ANPC1ALDH1A1MAPT
SCHEMBL7932874 0.74 PNMT (0.33) PNMTRAB9ANPC1
SCHEMBL8160178 0.72 NPC1 (0.41) PNMTRAB9ANPC1ALDH1A1MAPT
SCHEMBL7930557 0.70 PNMT (0.36) PNMTRAB9ANPC1DRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0554574-B1 Process for producing a styrenic polymer and a catalyst for use therein IDEMITSU KOSAN CO (JP) 2001-03-07 EP disclosed
US-RE37064-E1 Process for producing styrenic polymer IDEMITSU KOSAN CO., LTD. (JP) 2001-02-20 US disclosed
US-6100352-A USING A CATALYST CONSISTING OF A TRANSITION METAL COMPOUND, A COMPOUND CAPABLE OF FORMING AN IONIC COMPOUND BY REACTING WITH THE TRANSITION METAL COMPOUND OR AN OXYGEN-CONTAINING COMPOUND SUCH AS ALUMINOXANE IDEMITSU KOSAN CO., LTD. (JP) 2000-08-08 US disclosed
EP-0757064-B1 STYRENE POLYMER AND MOLDED ARTICLES IDEMITSU PETROCHEMICAL CO (JP) 2000-05-17 EP disclosed
EP-0988957-A1 Process for preparing a styrenic resin IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2000-03-29 EP disclosed
EP-0810238-B1 A process for producing polymer IDEMITSU KOSAN CO (JP) 2000-02-02 EP disclosed
US-5905126-A Process and catalyst for producing styrenic polymer IDEMITSU KOSAN CO., LTD. (JP) 1999-05-18 US disclosed
EP-0707014-B1 PROCESS FOR PRODUCING AROMATIC VINYL COMPOUND COPOLYMER IDEMITSU KOSAN CO (JP) 1999-02-17 EP disclosed
US-5786433-A Process for producing styrenic polymer IDEMITSU KOSAN CO., LTD. (JP) 1998-07-28 US disclosed
EP-0659775-B1 Process for producing styrenic polymer IDEMITSU KOSAN CO (JP) 1998-07-01 EP disclosed
EP-0584646-A2 Process for producing styrenic polymer IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-03-02 EP disclosed
EP-0566068-A2 Process for purification of styrenic polymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-10-20 EP disclosed
EP-0554574-A1 Process for producing a styrenic polymer and a catalyst for use therein IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-08-11 EP disclosed
EP-0543022-A1 PROCESS FOR PRODUCING STYRENIC POLYMER AND CATALYST THEREFOR IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-05-26 EP disclosed
EP-0535582-A1 Process for producing styrenic polymer IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1993-04-07 EP disclosed
EP-0505890-A2 Process for producing a styrenic polymer and a catalyst for use therein IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
EP-0505973-A2 Process for producing styrenic copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
EP-0505972-A2 Process for producing styrenic copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
EP-0497207-A2 Process for purification of styrenic polymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-08-05 EP disclosed
EP-0492282-A1 Process for producing a styrene polymer and a catalyst for use therein IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-07-01 EP disclosed