SCHEMBL7756029

SCHEMBL7756029

CCN(CC)c1ccc(NC2(NC(C)=O)C(=O)N(c3ccccc3)N=C2Cc2ccccc2)c(C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFER P55789 5/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPT P10636 13/20 0.41
SMN1; SMN2 Q16637 5/20 0.41
TP53 P04637 1/20 0.41
HTT P42858 2/20 0.41
RPS6KA2 Q15349 1/20 0.39
MAPK1 P28482 4/20 0.38
HCRTR1 O43613 1/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP2C19 P33261 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
CYP1A2 P05177 1/20 0.37
HSD17B10 Q99714 3/20 0.36
RXFP1 Q9HBX9 1/20 0.36
ALOX15 P16050 2/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7756010 0.89 MAPT (0.44) GFERMEN1KMT2AMAPTSMN1; SMN2
SCHEMBL7759716 0.87 NOX1 (0.41) MEN1KMT2AMAPTSMN1; SMN2TP53
SCHEMBL7756100 0.86 MAPT (0.42) GFERMEN1KMT2AMAPTSMN1; SMN2
SCHEMBL7761055 0.84 RPS6KA2 (0.41) GFERMEN1KMT2AMAPTSMN1; SMN2
SCHEMBL9400524 0.83 GFER (0.46) GFERMEN1KMT2AMAPTSMN1; SMN2
SCHEMBL9400418 0.82 GFER (0.45) GFERMEN1KMT2AMAPTSMN1; SMN2
SCHEMBL7762390 0.81 RPS6KA2 (0.40) GFERMEN1KMT2AMAPTSMN1; SMN2
SCHEMBL7760663 0.81 MAPT (0.37) MEN1KMT2AMAPTSMN1; SMN2MAPK1
SCHEMBL7762395 0.80 CNR2 (0.36) MEN1KMT2AMAPTHTTALDH1A1
Dimethylamine SCHEMBL7760667 0.80 MEN1 (0.38) MEN1KMT2AMAPTSMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0665462-B1 Thermofixable photosensitive recording material and process for preparing thereof NEW OJI PAPER CO LTD (JP) 2001-04-18 EP disclosed
US-5565306-A SUBSTRATE HAVING RECORDING LAYER CONTAINING PYRAZOLONE DERIVATIVE, HYDROQUINONE DERIVATIVE, ACIDIC SUBSTANCE MUTUALLY DISSOLVED THEREIN NEW OJI PAPER CO., LTD. (JP) 1996-10-15 US disclosed
EP-0665462-A1 Thermofixable photosensitive recording material and process for preparing thereof NEW OJI PAPER CO., LTD. (JP) 1995-08-02 EP disclosed