Dimethylamine

Dimethylamine

SCHEMBL7760667

CC(=O)NC1(Nc2ccccc2)C(=O)N(c2ccccc2)N=C1Cc1ccccc1.CNC

nearest known ligand 0.38

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
PTPN1 P18031 1/20 0.34
MAPK14 Q16539 2/20 0.34
ALDH1A1 P00352 5/20 0.33
GAA P10253 3/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
CES2 O00748 1/20 0.33
ELANE P08246 1/20 0.33
RNASEH1 O60930 2/20 0.33
USP2 O75604 1/20 0.33
ALOX15 P16050 1/20 0.33
MAPK1 P28482 1/20 0.33
POLB P06746 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 1/20 0.33
MAPT P10636 1/20 0.33
MAPK13 O15264 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethylamine SCHEMBL7759719 0.94 MEN1 (0.35) MEN1KMT2APTPN1MAPK14ALDH1A1
SCHEMBL7760663 0.90 MAPT (0.37) MEN1KMT2AALDH1A1GAAL3MBTL1
SCHEMBL7759716 0.89 NOX1 (0.41) MEN1KMT2APTPN1ALDH1A1GAA
Dimethylamine SCHEMBL7759251 0.84 SMN1; SMN2 (0.44) MEN1KMT2AALDH1A1GAAL3MBTL1
Diethylamine SCHEMBL7759239 0.84 MEN1 (0.34) MEN1KMT2APTPN1MAPK14ALDH1A1
Diethylamine SCHEMBL7762398 0.83 L3MBTL1 (0.38) MEN1KMT2AMAPK14L3MBTL1
Diethylamine SCHEMBL7759226 0.83 HSD17B10 (0.34) MEN1KMT2AMAPK14ALDH1A1CES2
Dimethylamine SCHEMBL8973174 0.81 MEN1 (0.39) MEN1KMT2AALDH1A1GAAL3MBTL1
SCHEMBL7759221 0.80 CNR2 (0.40) MEN1KMT2AALDH1A1L3MBTL1POLB
SCHEMBL7759232 0.79 CNR2 (0.41) MEN1KMT2APTPN1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0665462-B1 Thermofixable photosensitive recording material and process for preparing thereof NEW OJI PAPER CO LTD (JP) 2001-04-18 EP disclosed
US-5565306-A SUBSTRATE HAVING RECORDING LAYER CONTAINING PYRAZOLONE DERIVATIVE, HYDROQUINONE DERIVATIVE, ACIDIC SUBSTANCE MUTUALLY DISSOLVED THEREIN NEW OJI PAPER CO., LTD. (JP) 1996-10-15 US disclosed
EP-0665462-A1 Thermofixable photosensitive recording material and process for preparing thereof NEW OJI PAPER CO., LTD. (JP) 1995-08-02 EP disclosed