SCHEMBL7756174

SCHEMBL7756174

CCC[SiH]1CCC(C2CCC(c3ccc(-c4ccc(F)c(F)c4)cc3)CC2)CC1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
DRD2 P14416 1/20 0.31
P2RY14 Q15391 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7756494 1.00 CYP17A1 (0.31) CYP17A1CYP11B1CYP11B2DRD2P2RY14
SCHEMBL7756169 1.00 CYP17A1 (0.31) CYP17A1CYP11B1CYP11B2DRD2P2RY14
SCHEMBL7757568 0.92 CYP11B2 (0.34) CYP17A1CYP11B1CYP11B2DRD2P2RY14
SCHEMBL7757564 0.92 CYP11B2 (0.34) CYP17A1CYP11B1CYP11B2DRD2P2RY14
SCHEMBL7757296 0.92 SPHK1 (0.34) P2RY14
SCHEMBL7756609 0.92 SPHK1 (0.34) P2RY14
SCHEMBL7756604 0.92 SPHK1 (0.34) P2RY14
SCHEMBL7756657 0.90 CTSC (0.30)
SCHEMBL8771564 0.90 CTSC (0.30)
SCHEMBL7756655 0.90 CTSC (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718387-B1 A liquid crystal composition and a liquid crystal display element which contains it SHINETSU CHEMICAL CO (JP) 2001-03-14 EP disclosed
EP-0713878-B1 A method of manufacturing a trans silacyclohexane compound SHINETSU CHEMICAL CO (JP) 2000-02-16 EP disclosed
EP-0670322-B1 A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it SHINETSU CHEMICAL CO (JP) 2000-01-19 EP disclosed
US-5762826-A Liquid crystal composition and a liquid crystal display element which contains it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-06-09 US disclosed
US-5730901-A Silacyclohexane compounds, preparation thereof liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-03-24 US disclosed
US-5582764-A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-12-10 US disclosed
US-5560866-A Process for preparing silacyclohexane compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-10-01 US disclosed
EP-0732335-A1 Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-09-18 EP disclosed
EP-0718387-A1 A liquid crystal composition and a liquid crystal display element which contains it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-06-26 EP disclosed
US-5523439-A Process for preparing silacyclohexane compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-06-04 US disclosed
EP-0713878-A1 A method of manufacturing a trans silacyclohexane compound Shin-Etsu Chemical Co., Ltd. (JP) 1996-05-29 EP disclosed
EP-0696592-A1 Process for preparing silacyclohexane compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-02-14 EP disclosed
EP-0688776-A2 Process for preparing silacyclo-hexane compounds Shin-Etsu Chemical Co., Ltd. (JP) 1995-12-27 EP disclosed
EP-0670322-A1 A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it Shin-Etsu Chemical Co., Ltd. (JP) 1995-09-06 EP disclosed