Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.35 |
| ▸ | S100A10 | P60903 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TK1 | P04183 | 2/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756562 | 1.00 | TSHR (0.37) | TSHRTP53KDM4EPKMMAPT | |
| SCHEMBL7258543 | 0.87 | ALDH1A1 (0.38) | KDM4EMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL7759873 | 0.85 | ALDH1A1 (0.36) | TSHRTP53KDM4EMAPTLMNA | |
| SCHEMBL7759871 | 0.85 | ALDH1A1 (0.36) | TSHRTP53KDM4EMAPTLMNA | |
| SCHEMBL7758268 | 0.84 | TP53 (0.36) | TSHRTP53KDM4EMAPTLMNA | |
| SCHEMBL7758263 | 0.84 | TP53 (0.36) | TSHRTP53KDM4EMAPTLMNA | |
| SCHEMBL9009374 | 0.83 | TP53 (0.38) | TSHRTP53KDM4EPKMMAPT | |
| SCHEMBL7757660 | 0.81 | TSHR (0.36) | TSHRTP53KDM4EMAPTLMNA | |
| SCHEMBL7757657 | 0.81 | TSHR (0.36) | TSHRTP53KDM4EMAPTLMNA | |
| SCHEMBL7758839 | 0.81 | TP53 (0.37) | TSHRTP53KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736015-B1 | ANTIVIRAL 2,4-PYRIMIDINDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2001-03-07 | — | — | EP | disclosed |
| US-5747500-A | VIRICIDES FOR AIDS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-05-05 | — | — | US | disclosed |
| WO-1995018109-A1 | NOVEL ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-07-06 | — | — | WO | disclosed |