Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 6/20 | 0.44 |
| ▸ | SLK | Q9H2G2 | 4/20 | 0.43 |
| ▸ | STK10 | O94804 | 3/20 | 0.43 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL815228 | 0.90 | CHEK1 (0.51) | CHEK1PGRSLKSTK10XDH | |
| SCHEMBL12509754 | 0.89 | CHEK1 (0.52) | CHEK1PGRSLKSTK10XDH | |
| SCHEMBL12509906 | 0.88 | CHEK1 (0.51) | CHEK1PGRSLKSTK10XDH | |
| SCHEMBL12577698 | 0.86 | CHEK1 (0.47) | CHEK1PGRSLKSTK10XDH | |
| SCHEMBL12640589 | 0.86 | CHEK1 (0.47) | CHEK1PGRSLKSTK10XDH | |
| SCHEMBL7492741 | 0.85 | MAOA (0.44) | PSDGSK3BMEN1LMNAMAPT | |
| SCHEMBL7488025 | 0.85 | CYP11B1 (0.39) | PGRSLKSTK10PSDLMNA | |
| SCHEMBL12509969 | 0.84 | CHEK1 (0.45) | CHEK1PGRSLKSTK10XDH | |
| SCHEMBL12425045 | 0.83 | PTPN5 (0.48) | CHEK1PGRSLKPTGDR2 | |
| SCHEMBL13204641 | 0.82 | GSK3B (0.52) | PGRGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765919-B1 | Monophasic solid solutions with asymmetrical pyrrolo-(4-3-c)-pyrroles as host | CIBA SC HOLDING AG (CH) | 2001-02-21 | — | — | EP | disclosed |
| US-5756746-A | KETOPYRROLES AND QUINACRIDONES FOR LIGHT STABLE AND WEATHER RESISTANT COLOR COMPOSITIONS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0765919-A2 | Monophasic solid solutions with asymmetrical pyrrolo-(4-3-c)-pyrroles as host | Ciba SC Holding AG (CH) | 1997-04-02 | — | — | EP | disclosed |