SCHEMBL7756597

SCHEMBL7756597

[CH2]CCC=CC(=O)OCCCC

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.66
HCAR2 Q8TDS4 4/20 0.58
HPGD P15428 1/20 0.56
TSHR P16473 1/20 0.56
MAPT P10636 2/20 0.50
RAB9A P51151 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
APP P05067 5/20 0.47
ALDH1A1 P00352 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7750747 0.95 HCAR2 (0.59) ATMHCAR2HPGDTSHRMAPT
SCHEMBL7756679 0.93 HCAR2 (0.60) ATMHCAR2HPGDTSHRMAPT
SCHEMBL7756691 0.89 HCAR2 (0.55) ATMHCAR2HPGDTSHRMAPT
SCHEMBL6661633 0.87 ATM (0.73) ATMHCAR2HPGDTSHRMAPT
SCHEMBL11843058 0.87 ATM (0.73) ATMHCAR2HPGDTSHRMAPT
SCHEMBL1876004 0.87 ATM (0.73) ATMHCAR2HPGDTSHRMAPT
SCHEMBL6661635 0.87 ATM (0.73) ATMHCAR2HPGDTSHRMAPT
SCHEMBL28235598 0.87 ATM (0.58) ATMHCAR2HPGDTSHRMAPT
SCHEMBL10481293 0.85 ATM (0.70) ATMHCAR2HPGDTSHRMAPT
SCHEMBL10481292 0.85 ATM (0.70) ATMHCAR2HPGDTSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0835248-B1 1-AMINO-3-BENZYLURACILS BASF AG (DE) 2001-02-21 EP disclosed
CN-1189824-A 1-amino-3-benzyluracils BASF AG (DE) 1998-08-05 CN disclosed