Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750747 | 0.98 | HCAR2 (0.59) | HCAR2ATMAPPTSHRHPGD | |
| SCHEMBL7756597 | 0.93 | ATM (0.66) | HCAR2ATMAPPTSHRHPGD | |
| SCHEMBL11825918 | 0.88 | HCAR2 (0.71) | HCAR2ATMAPPTSHRHPGD | |
| SCHEMBL8032532 | 0.88 | HCAR2 (0.66) | HCAR2ATMAPPNAAAMAPT | |
| SCHEMBL3016477 | 0.88 | HCAR2 (0.66) | HCAR2ATMAPPNAAAMAPT | |
| SCHEMBL15365968 | 0.88 | HCAR2 (0.66) | HCAR2ATMAPPNAAAMAPT | |
| SCHEMBL1852690 | 0.88 | HCAR2 (0.66) | HCAR2ATMAPPNAAAMAPT | |
| SCHEMBL15366125 | 0.88 | HCAR2 (0.66) | HCAR2ATMAPPNAAAMAPT | |
| SCHEMBL21065507 | 0.88 | HCAR2 (0.71) | HCAR2ATMAPPTSHRHPGD | |
| SCHEMBL10857755 | 0.88 | HCAR2 (0.66) | HCAR2ATMAPPNAAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835248-B1 | 1-AMINO-3-BENZYLURACILS | BASF AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| CN-1189824-A | 1-amino-3-benzyluracils | BASF AG (DE) | 1998-08-05 | — | — | CN | disclosed |
| EP-0835248-A1 | 1-AMINO-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997001543-A1 | 1-AMINO-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-01-16 | — | — | WO | disclosed |