SCHEMBL775678

SCHEMBL775678

Cc1cccc(C(=O)SC(=O)c2cccc(C)c2C)c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
HSD17B10 Q99714 3/20 0.45
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
HPGD P15428 2/20 0.45
KMT2A Q03164 3/20 0.44
TRPA1 O75762 2/20 0.44
LMNA P02545 2/20 0.44
MEN1 O00255 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2C9 P11712 2/20 0.44
AKR1B10 O60218 1/20 0.44
ABCB11 O95342 1/20 0.44
DHFR P00374 1/20 0.44
MPO P05164 1/20 0.44
CYP1A2 P05177 1/20 0.44
CHRM1 P11229 1/20 0.44
AKR1B1 P15121 1/20 0.44
PTGS1 P23219 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29026507 0.85 ESR1 (0.50) ESR1ESR2HSD17B10KDM4EALDH1A1
SCHEMBL30797844 0.82 HPGD (0.48) HSD17B10KDM4EALDH1A1HPGDKMT2A
SCHEMBL774644 0.82 HPGD (0.48) HSD17B10KDM4EALDH1A1HPGDKMT2A
SCHEMBL29272521 0.80 ESR1 (0.46) ESR1ESR2HSD17B10KDM4EALDH1A1
SCHEMBL9864607 0.79 ESR1 (0.52) ESR1ESR2HSD17B10KDM4EALDH1A1
SCHEMBL310386 0.79 KMT2A (0.52) ESR1ESR2HSD17B10KDM4EALDH1A1
SCHEMBL29515031 0.79 KMT2A (0.52) ESR1ESR2HSD17B10KDM4EALDH1A1
SCHEMBL7767069 0.79 ESR1 (0.41) ESR1ESR2HSD17B10KDM4EALDH1A1
SCHEMBL31519420 0.77 ESR1 (0.50) ESR1ESR2HSD17B10KDM4EALDH1A1
SCHEMBL56188 0.77 ALDH1A1 (0.65) ESR1ESR2HSD17B10KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9343777-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-17 US disclosed
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed