SCHEMBL7757000

SCHEMBL7757000

C=C(C)c1cccc(C(C)O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
UGT2B7 P16662 1/20 0.42
BRD4 O60885 1/20 0.41
BRD2 P25440 1/20 0.41
CREBBP Q92793 1/20 0.41
GBA1 P04062 1/20 0.40
PTGS1 P23219 3/20 0.40
PTGS2 P35354 3/20 0.40
MAPT P10636 2/20 0.40
CXCR1 P25024 2/20 0.40
CXCR2 P25025 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 2/20 0.40
HPGD P15428 2/20 0.40
LMNA P02545 2/20 0.40
RECQL P46063 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL299924 0.86 MAPT (0.46) GBA1PTGS1PTGS2MAPTCXCR1
SCHEMBL31529664 0.86 MAPT (0.46) GBA1PTGS1PTGS2MAPTCXCR1
SCHEMBL7977708 0.84 GBA1 (0.40) GBA1PTGS1PTGS2MAPTCXCR1
SCHEMBL20327221 0.84 GBA1 (0.43) GBA1PTGS1PTGS2MAPTCXCR1
SCHEMBL10981458 0.81 PTGS1 (0.45) MEN1KMT2AUGT2B7BRD4BRD2
SCHEMBL11816271 0.80 MEN1 (0.56) MEN1KMT2AUGT2B7PTGS1PTGS2
SCHEMBL12614429 0.79 CYP3A4 (0.39) MEN1KMT2AGBA1PTGS1PTGS2
SCHEMBL5165244 0.79 GBA1 (0.43) GBA1PTGS1PTGS2MAPTCXCR1
SCHEMBL1079641 0.79 GBA1 (0.38) MEN1KMT2AGBA1PTGS1PTGS2
SCHEMBL9245208 0.78 TAAR1 (0.50) GBA1PTGS1PTGS2MAPTCXCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1077392-A1 Photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2001-02-21 EP disclosed