Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299924 | 0.86 | MAPT (0.46) | GBA1SMN1; SMN2PTGS1PTGS2MAPT | |
| SCHEMBL31529664 | 0.86 | MAPT (0.46) | GBA1SMN1; SMN2PTGS1PTGS2MAPT | |
| SCHEMBL20327221 | 0.84 | GBA1 (0.43) | GBA1SMN1; SMN2PTGS1PTGS2MAPT | |
| SCHEMBL7757000 | 0.84 | MEN1 (0.43) | GBA1SMN1; SMN2PTGS1PTGS2MAPT | |
| SCHEMBL5165244 | 0.79 | GBA1 (0.43) | GBA1SMN1; SMN2PTGS1PTGS2MAPT | |
| SCHEMBL12614429 | 0.79 | CYP3A4 (0.39) | GBA1SMN1; SMN2PTGS1PTGS2MAPT | |
| SCHEMBL16960791 | 0.78 | ANPEP (0.54) | SMN1; SMN2PTGS1PTGS2MAPTALDH1A1 | |
| SCHEMBL9245208 | 0.78 | TAAR1 (0.50) | GBA1SMN1; SMN2PTGS1PTGS2MAPT | |
| SCHEMBL1345165 | 0.78 | PTGS2 (0.68) | SMN1; SMN2PTGS1PTGS2MAPTALDH1A1 | |
| SCHEMBL167439 | 0.78 | FURIN (0.43) | MAPTLMNAHTTL3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040193-A1 | METHOD FOR THE SYNTHESIS OF PYRAZOLINES | CHEMRX ADVANCED TECHNOLOGIES, INC. (US) | 2001-06-07 | — | — | WO | claimed |
| WO-2001040193-A1 | METHOD FOR THE SYNTHESIS OF PYRAZOLINES | CHEMRX ADVANCED TECHNOLOGIES, INC. (US) | 2001-06-07 | — | — | WO | disclosed |
| EP-0881250-B1 | Process for preparing organosilicon compounds having hydrogen bound to silicon | WACKER CHEMIE GMBH (DE) | 1999-11-24 | — | — | EP | disclosed |
| US-5866707-A | Process for preparing organosilicon compounds having Si-bonded hydrogen atoms | WACKER-CHEMIE GMBH (DE) | 1999-02-02 | — | — | US | disclosed |
| EP-0881250-A1 | Process for preparing organosilicon compounds having hydrogen bound to silicon | Wacker-Chemie GmbH (DE) | 1998-12-02 | — | — | EP | disclosed |