Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23952236 | 0.86 | ALDH1A1 (0.48) | ALDH1A1LMNAHTTPOLBKMT2A | |
| SCHEMBL9313018 | 0.85 | POLB (0.50) | ALDH1A1LMNAGAAPOLBKMT2A | |
| SCHEMBL7754190 | 0.85 | CA1 (0.51) | ALDH1A1LMNAHTTPOLBKMT2A | |
| SCHEMBL18088626 | 0.85 | ALDH1A1 (0.47) | ALDH1A1HTTPOLBKMT2ANPC1 | |
| SCHEMBL5888424 | 0.82 | POLB (0.56) | ALDH1A1LMNAHTTGAAPOLB | |
| SCHEMBL774588 | 0.82 | POLB (0.56) | ALDH1A1LMNAHTTGAAPOLB | |
| SCHEMBL14561875 | 0.81 | POLB (0.53) | ALDH1A1LMNAPOLBKMT2ANPC1 | |
| SCHEMBL7076639 | 0.81 | CA1 (0.51) | ALDH1A1LMNAHTTPOLBKMT2A | |
| SCHEMBL18622116 | 0.81 | ALDH1A1 (0.49) | ALDH1A1LMNAHTTPOLBKMT2A | |
| SCHEMBL10894126 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNAHTTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704539-B1 | Chemiluminescent reagent and assay using a substituted acetanilide for light generation | JOHNSON & JOHNSON CLIN DIAG (US) | 2001-02-28 | — | — | EP | disclosed |
| US-5705357-A | DETECTING PEROXIDASE; SENSITIVITY, LOW BACKGROUND; MEDICAL DIAGNOSIS | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1998-01-06 | — | — | US | disclosed |
| EP-0704539-A2 | Chemiluminescent reagent and assay using a substituted acetanilide for light generation | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1996-04-03 | — | — | EP | disclosed |