SCHEMBL7757113

SCHEMBL7757113

O=C(O)c1c(O)c(I)c(I)c(C(=O)O)c1I

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
GLRA3 O75311 1/20 0.32
GLRB P48167 1/20 0.32
TPMT P51580 1/20 0.32
CYP1A2 P05177 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27397979 0.92 DPP4 (0.36) DPP4CA12CA1CA2CA7
SCHEMBL19678531 0.89 DPP4 (0.37) DPP4CA12CA1CA2CA7
SCHEMBL7757117 0.83 DPP4 (0.37) DPP4CA12CA1CA2CA7
SCHEMBL5586281 0.83 DPP4 (0.37) DPP4CA12CA1CA2CA7
SCHEMBL8537633 0.83 TPMT (0.38) CA12CA1CA2CA7CA9
SCHEMBL4587818 0.83 TPMT (0.41) DPP4CA12CA1CA2CA7
SCHEMBL7596897 0.83 TPMT (0.41) DPP4CA12CA1CA2CA7
Hydrochloric Acid SCHEMBL8536294 0.80 TPMT (0.36) CA12CA1CA2CA7CA9
SCHEMBL9600105 0.80 TPMT (0.39) DPP4CA12CA1CA2CA7
Hydrochloric Acid SCHEMBL9787611 0.80 TPMT (0.39) DPP4CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001058848-A1 A PROCESS FOR THE PURIFICATION OF 3-AMINO-1,2-PROPANEDIOL AND 2-AMINO-1,3-PROPANEDIOL BRACCO IMAGING S.P.A. (IT) 2001-08-16 WO disclosed