SCHEMBL8537633

SCHEMBL8537633

O=C(O)c1c(I)c(I)c(I)c(C(=O)O)c1I

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TPMT P51580 2/20 0.38
CYP1A2 P05177 1/20 0.36
LMNA P02545 1/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8536294 0.97 TPMT (0.36) TPMTCYP1A2LMNACA12CA1
SCHEMBL1859003 0.97 TPMT (0.39) TPMTCYP1A2LMNACA12CA1
Hydrochloric Acid SCHEMBL8824728 0.93 TPMT (0.38) TPMTCYP1A2LMNACA12CA1
SCHEMBL7596897 0.93 TPMT (0.41) TPMTCYP1A2LMNACA12CA1
SCHEMBL4587818 0.93 TPMT (0.41) TPMTCYP1A2LMNACA12CA1
SCHEMBL9600105 0.90 TPMT (0.39) TPMTCYP1A2LMNACA12CA1
SCHEMBL4265757 0.90 TPMT (0.39) TPMTCYP1A2LMNACA12CA1
Hydrochloric Acid SCHEMBL9787611 0.90 TPMT (0.39) TPMTCYP1A2LMNACA12CA1
Hydrochloric Acid SCHEMBL8541347 0.90 TPMT (0.39) TPMTCYP1A2LMNACA12CA1
SCHEMBL8855992 0.90 TPMT (0.39) TPMTCYP1A2LMNACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250228774-A1 SYSTEMS AND METHODS FOR ACCELERATED HYDROLYSIS OF POLYSACCHARIDE-BASED HYDROGELS BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-07-17 US disclosed
WO-2025100238-A1 EPOXY COMPOUND AND USE THEREOF 四国化成工業株式会社 2025-05-15 WO disclosed
US-20250136760-A1 AMINO-ACID- AND AMINO-ALCOHOL-BASED POLYAMINE COMPOUNDS AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-05-01 US disclosed
US-5851511-A Polyiodo compounds, their preparation and their use in X-ray radiology GUERBET S.A. (FR) 1998-12-22 US disclosed
US-5693311-A Polyiodinated compounds, process for preparing them and diagnostic compositions GUERBET S.A. (FR) 1997-12-02 US disclosed
US-4053510-A REACTING A DICARBOXYLIC ACID WITH UREA IN CHLOROSULFONIC ACID OR OLEUM AKZO N.V. (NL) 1977-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250228774-A1 SYSTEMS AND METHODS FOR ACCELERATED HYDROLYSIS OF POLYSACCHARIDE-BASED HYDROGELS MGAM, SI, AGL TPMT 4651/4885CYP1A2 2436/4885LMNA 2099/4885
US-20250136760-A1 AMINO-ACID- AND AMINO-ALCOHOL-BASED POLYAMINE COMPOUNDS AND MEDICAL HYDROGELS FORMED THEREFROM CARM1, PNMT, ADM2 TPMT 3851/4885CYP1A2 2052/4885LMNA 4080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.