Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.78 |
| ▸ | ADORA3 | P0DMS8 | 18/20 | 0.78 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.78 |
| ▸ | ADORA2B | P29275 | 10/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651022 | 1.00 | ADORA2A (0.78) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7651032 | 1.00 | ADORA2A (0.78) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7757121 | 1.00 | ADORA2A (0.78) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7651038 | 1.00 | ADORA2A (0.78) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7088617 | 0.89 | ADORA2A (0.79) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL1978553 | 0.89 | ADORA2A (0.79) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL1982788 | 0.89 | ADORA2A (0.79) | ADORA2AADORA3ADORA1ADORA2B | |
| Gw-328267 SCHEMBL1983126 | 0.87 | ADORA2A (1.00) | ADORA2AADORA3ADORA1ADORA2B | |
| Gw-328267 SCHEMBL1979140 | 0.87 | ADORA2A (1.00) | ADORA2AADORA3ADORA1ADORA2B | |
| Gw-328267 SCHEMBL13268529 | 0.87 | ADORA2A (1.00) | ADORA2AADORA3ADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090022-A1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067265-A1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-12-29 | — | — | WO | disclosed |